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All Journal Jurnal Agroindustri INDONESIAN JOURNAL OF PHARMACY Jurnal Penelitian Pendidikan Kimia PUBLIKASI PENELITIAN TERAPAN DAN KEBIJAKAN Clarias : Jurnal Perikanan Air Tawar
Rindit Pambayun
Department Of Agricultural Technology, Faculty Of Agriculture Sriwijaya University Jalan Palembang Prabumulih, Km. 32 Indralaya OKI
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Journal : INDONESIAN JOURNAL OF PHARMACY

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Phenolic content and antibacterial properties of various extracts of gambir (Uncaria gambir Roxb) Rindit Pambayun; Murdijati Gardjito; Slamet Sudarmadji; Kapti Rahayu Kuswanto
Indonesian Journal of Pharmacy Vol 18 No 3, 2007
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.053 KB) | DOI: 10.14499/indonesianjpharm0iss0pp141-146

Abstract

Extraction of gambir product with various solvents gave vary in amount of yields, phenolic contents, and its antibacterial properties. Extraction was performed by maseration and Soxhlet methods with some solvents; chloroform, ethyl acetate, ethanol, water, and their combination. The results showed that the highest yield of extract obtained from the solvent combination of ethanol and water (1:1 v/v) both at the maseration and Soxhlet metods, i.e. 84.77 and 87.69 %, respectivelly. Soxhlet method gave the yield of extract higher than that of maseration method. The highest phenolic content was found at the extracts using ethyl acetate both in maseration and soxlet methods, i.e. 88,30 and 90,85 %, respectivelly. Antobacterial properties on the Gram-positive bacteria such as Streptococcus mutans, Staphylococcus aureus, and Bacillus subtilis, indicated that the extracts extracted by using ethyl acetate gave highest inhibitory properties. On the other hand, the extracts did not inhibit Gram-negative bacteria. Extraction was continued by using solvent combination of ethanol and water at the various proportion and at the three levels of temperature, 4, 30, and 60 °C. The results showed that solvent combination of ethanol and water (1:2), gave the highest yield of extracts but lower in phenolic contents and aantibacterial properties.Key words: antibacterial, phenolic content, extract of Uncaria gambir Roxb
Co-Authors . Parwiyanti Agus Wijaya Amin Rejo Budi Santoso Carles Carles Dedik Budianta Donny Prariska Eduan Rismansyah Gatot Priyanto Guttifera Kapti Rahayu Kuswanto Murdijati Gardjito Railia Karneta Rizki Eka Puteri Puteri Selly Ratna Sari Slamet Sudarmadji