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All Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Aryando Pradana
Faculty of Medicine University of Indonesia/ Dr. Cipto Mangunkusumo Hospital Jakarta
Health Professions Medicine & Pharmacology Public Health

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 1 
Lamellar Body Count has Higher Sensitivity and Specificity in the Prediction of Neonatal Respiratory Distress Syndrome Pradana, Aryando
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.778 KB)

Abstract

Objective: The study was designed to acquire the cut-off value for lamellar body count and its role in predicting the presence of Respiratory Distress Syndrome (RDS) in pregnancy with gestational age above 28 weeks. Method: Amniotic fluid specimens were collected by amniotomy during cesarean section from women with gestational age above 28 weeks. A haematology analyzer (Advia 120) was used to determine the lamellar body counts. We also performed foam stability test and observed the development of respiratory distress syndrome. Receiver operating characteristics curve was estimated to assess the threshold of lamellar bodies count that may predict the presence of Respiratory Distress Syndrome. Result: Fifty nine specimens were collected from woman with 29 - 42 weeks gestational age. The incidence of Respiratory Distress Syndrome was 15.3%. Area under the curve for lamellar body count was 0.94. Lamellar body count, with the best cut-off point of 50,000 cell/μl had sensitivity 89% and specifity 92% for predicting the presence of RDS, while the sensitivity of foam stability test was 67% and specificity was 90%. The negative predictive value of the lamellar body count was 98% slightly better than the negative predictive value of the foam stability test 94 %. Conclusion: Although both test are good predictor of RDS, lamellar body count has higher sensitivity and specificity. It also has more advantages as it only requires small amount of sample, fast, easy and more objective. [Indones J Obstet Gynecol 2012; 36-4: 176-80] Keywords: foam stability test, lamellar body, respiratory distress syndrome
Management Therapy in Chronic Ectopic Pregnancy Pradana, Aryando
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 4, October 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.177 KB)

Abstract

Objective: Improving skill in making a diagnosis and management therapy in chronic ectopic pregnancy. Method: Case Report. Conclusion: Diagnosis of chronic EP is difficult to establish before surgery. Conservative treatment using medication (methotrexate) can not be applied to chronic EP because the β-hCG level is difficult to be detected. [Indones J Obstet Gynecol 2010; 34-4: 199-203] Keywords: ectopic pregnancy, chronic ectopic pregnancy
Severe Complication of Uterine Perforation and Ileum Prolapse after Having Unsafe Abortion Pradana, Aryando
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 3, July 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.254 KB)

Abstract

Objective: Discuss complication after unsafe abortion and management of uterine perforation after curettage. Methods: Case report. Conclusion: Uterine perforation and ileum prolapse in this patient was a complication from unsafe abortion from unregistered health practicioner, fortunately the outcome is good, although actually it could be prevent. [Indones J Obstet Gynecol 2012; 36-3:150-3] Keywords: hysteroraphy, ileum anastomose, ileum laceration, ileum prolapse, ileum resection, incomplete abortion, uterine perforation
CC-Human Menopausal Gonadotropin Combined with Growth Hormone in Mini-stimulation Protocol could Improve Clinical Outcome in Poor Ovarian Responders Polim, Arie A; Sini, Ivan R; Anwar, Indra NC; Pradana, Aryando; Kurniawati, Kurniawati; Fani, Erliana
Indonesian Journal of Obstetrics and Gynecology Volume. 3, no. 2, April 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (19.045 KB) | DOI: 10.32771/inajog.v3i2.43

Abstract

Objective: To investigate the role of CC-highly purified Human Menopausal Gonadotropin (hpHMG) and Growth Hormone (GH) in mini-stimulation protocol to improve outcome in poor ovarian responders (POR). Method: All patients were given clomiphene citrate 150 mg from day 3 to day 7 of menstrual cycle followed by 150 IU hpHMG daily from day 8 until ovulation trigger. Two groups were observed where one group received GH and the other arm did not. In the GH group, 8 IU of GH were given from day 1 of stimulation until stimulation was stopped. GnRH antagonist was used to suppress ovulation. Result: Among 51 eligible women, 29 patients with GH and 22 patients without GH, no difference was observed in the number of oocytes retrieved (2.21 versus 2.64) and the number of embryos transferred (1.24 versus 1.68) in the GH group versus the group without GH, respectively. Total clinical pregnancy rate was 17.6%. No significant difference in pregnancy and ongoing pregnancy rate in both groups (17.2% versus 18.2%) and (13.8% versus 13.6%), respectively. In patients older than 40 years old, GH showed a 4-fold likelihood in producing top quality embryos (44.8% vs 13.6%, OR=3.6, p=0.05). Conclusion: CC-HMG regimen in mini-stimulation protocol is an effective option in poor responders. Additional GH in ministimulation program provided a higher number of top quality embryos in women older than 40 years old, although there were no difference in clinical or ongoing pregnancy rate. Keywords: CC-HMG, growth hormone, IVF, mini-stimulation protocol, poor ovarian responders
Severe Complication of Uterine Perforation and Ileum Prolapse after Having Unsafe Abortion Pradana, Aryando
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 3, July 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.254 KB) | DOI: 10.32771/inajog.v36i3.316

Abstract

Objective: Discuss complication after unsafe abortion and management of uterine perforation after curettage. Methods: Case report. Conclusion: Uterine perforation and ileum prolapse in this patient was a complication from unsafe abortion from unregistered health practicioner, fortunately the outcome is good, although actually it could be prevent. [Indones J Obstet Gynecol 2012; 36-3:150-3] Keywords: hysteroraphy, ileum anastomose, ileum laceration, ileum prolapse, ileum resection, incomplete abortion, uterine perforation
Lamellar Body Count has Higher Sensitivity and Specificity in the Prediction of Neonatal Respiratory Distress Syndrome Pradana, Aryando
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (97.778 KB) | DOI: 10.32771/inajog.v36i4.321

Abstract

Objective: The study was designed to acquire the cut-off value for lamellar body count and its role in predicting the presence of Respiratory Distress Syndrome (RDS) in pregnancy with gestational age above 28 weeks. Method: Amniotic fluid specimens were collected by amniotomy during cesarean section from women with gestational age above 28 weeks. A haematology analyzer (Advia 120) was used to determine the lamellar body counts. We also performed foam stability test and observed the development of respiratory distress syndrome. Receiver operating characteristics curve was estimated to assess the threshold of lamellar bodies count that may predict the presence of Respiratory Distress Syndrome. Result: Fifty nine specimens were collected from woman with 29 - 42 weeks gestational age. The incidence of Respiratory Distress Syndrome was 15.3%. Area under the curve for lamellar body count was 0.94. Lamellar body count, with the best cut-off point of 50,000 cell/μl had sensitivity 89% and specifity 92% for predicting the presence of RDS, while the sensitivity of foam stability test was 67% and specificity was 90%. The negative predictive value of the lamellar body count was 98% slightly better than the negative predictive value of the foam stability test 94 %. Conclusion: Although both test are good predictor of RDS, lamellar body count has higher sensitivity and specificity. It also has more advantages as it only requires small amount of sample, fast, easy and more objective. [Indones J Obstet Gynecol 2012; 36-4: 176-80] Keywords: foam stability test, lamellar body, respiratory distress syndrome
Co-Authors Anwar, Indra NC Fani, Erliana Kurniawati Kurniawati Polim, Arie A Sini, Ivan R