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Idham Amir

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Author-ID : 3458562

Health Professions Medicine & Pharmacology

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Echocardiographic patterns in asphyxiated neonates Maswin Masyhur; Idham Amir; Sukman Tulus Putra; Alan Roland Tumbelaka
Paediatrica Indonesiana Vol 49 No 4 (2009): July 2009
Publisher : Indonesian Pediatric Society

Background Neonatal asphyxia is a disorder in neonates dueto decreased oxygenation (hypoxia) and decreased perfusion toorgans (ischemia). Duration of asphyxia and early managementinfluence the severity of organ dysfunction, including the heart.Objectives To obtain patterns of cardiac abnormality inneonatal asphyxia in Cipto Mangunkusumo Hospital withechocardiography. Design A cross-sectional study was performed on 22 asphyxiated neonates and 22 other non-asphyxiated neonates from March to October 2008. Inclusion criteria were term neonates, Apgar score :S 6 in the first minute for asphyxiated neonates and ?. 7 for normal/non-asphyxiated neonate. Echocardiographic examination was performed before the age of 48 hours.Results There were 7/22 asphyxiated neonates and 1/22 nonaxphyxiated neonate with heart disease (P <0.05). The mostcommon cardiac abnormality found in asphyxiated neonates waspatent ductus arteriosus, followed by atrial septal defect, tricuspid regurgitation, and pulmonary hypertension.Conclusion Cardiac abnormality is significantly found more oftenin asphyxiated than in non-asphyxiated neonates.

Nephrologic abnormalities in neonatal asphyxia at Cipto Mangunkusumo Hospital, Jakarta Idham Amir; Vera M Manoe; Taralan Tambunan
Paediatrica Indonesiana Vol 44 No 2 (2004): March 2004
Publisher : Indonesian Pediatric Society

Introduction Neonatal asphyxia is still the leading cause of highmorbidity and mortality in developed countries, as well as in devel-oping countries including Indonesia. As a response to asphyxia,renal hypoxia occurs which is initially temporary, but if persisting,can cause permanent damage to the cortex and medulla.Objective The purpose of this study was to determine thenephrologic abnormalities in neonatal asphyxia at CiptoMangunkusumo Hospital.Methods This was a cross sectional descriptive study conductedin the Division of Neonatology, Cipto Mangunkusumo Hospital fromAugust until November 2002. Neonates with congenital malforma-tion were excluded.Results The study showed that the incidence of nephrologic ab-normalities in neonatal asphyxia based on Apgar scores at 1, 5,and 10 minutes were 65/100, 26/33, and 5/6, respectively. The riskof nephrologic abnormalities was not statistically different in se-vere asphyxia compared to moderate asphyxia. Severe asphyxiaat 1 minute Apgar scores was correlated with the occurrence ofoliguria.Conclusion In asphyxiated newborn, it is very important to inves-tigate the possibility of nephrologic abnormalities

Periventricular leucomalacia in premature infants in neonatal ward, Cipto Mangunkusumo Hospital: A preliminary study Kemas Firman; Idham Amir; Nia Kurniati; Sudigdo Sastroasmoro
Paediatrica Indonesiana Vol 44 No 3 (2004): May 2004
Publisher : Indonesian Pediatric Society

Introduction Periventricular leucomalacia (PVL) is a major causeof neurodevelopment delay in premature infants, so early detec-tion of the preterm infant at high risk for the subsequent develop-ment of this lesion is critical.Objectives To determine the prevalence of PVL in premature in-fants hospitalized in neonatal ward, Cipto Mangunkusumo Hospi-tal using cranial ultrasound scans and define its characteristicsMethods Premature infants hospitalized in the neonatal ward fromJanuary to July 2003 were included in this study. Clinical featureswere retrieved from medical charts. Ultrasound scan was performedonce, after the age of 7 days and interpretations were read sepa-rately by two consultants of the radiology division.Results Fifty-one infants were included, 21 with <32-week gesta-tion, 30 with >32-week gestation; birth weight range were 1000 to2600 gram. Nineteen infants had cystic lesion and/or dilatation ofthe ventricle from the cranial ultrasound scan. The prevalence ofPVL in gestational age (GA) of <32 weeks was 6/21 and that in GAof >32 weeks was 13/30. Risk factors found in infants with PVLwere maternal infection, respiratory distress, sepsis and circula-tory failure.Conclusion The prevalence of PVL in preterm infants in CiptoMangunkusumo neonatal ward was higher than that was reportedin developed countries. Maternal infection, respiratory distress,sepsis, and circulatory failure which were commonly found in theseinfants were factors to be considered as risks for PVL

Urinary tract infection among neonatal sepsis of late-onset in Cipto Mangunkusumo Hospital Novie Amelia; Idham Amir; Partini P Trihono
Paediatrica Indonesiana Vol 45 No 5 (2005): September 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.5.2005.217-22

Background Urine culture, as part of a full septic work-up forlate-onset neonatal sepsis, was not routinely done in the Neona-tal Ward at Cipto Mangunkusumo Hospital, and as of today, theprevalence of urinary tract infection (UTI) among neonates withlate-onset sepsis remains unknown.Objectives To determine the prevalence and microbiological pat-terns of UTI among late-onset neonatal sepsis in CiptoMangunkusumo Hospital.Methods We conducted a cross-sectional study on all neonatesdiagnosed as suspected late-onset sepsis who underwent sep-sis evaluation between 20 October 2003 â€“ 30 April 2004. Urinespecimens were collected by bladder catheterization for cultureand urinalysis.Results UTI was found in 14.9% (7/47) neonates who under-went urine culture (male: female ratio was 5:2). Six subjectswho had UTI were preterm neonates, Klebsiella pneumoniaewas found in both blood and urine cultures of 1 subject, while theothers showed different microorganisms. Forty-five out of 47subjects, who were suspected of late-onset sepsis, had posi-tive blood cultures. All subjects with UTI had positive bacteriuriafrom Gram-stained specimen.Conclusions The prevalence of UTI among neonates with late-onset sepsis in Cipto Mangunkusumo Hospital was 14.9%. Themicroorganisms most frequently found in urine cultures werePseudomonas sp., Staphylococcus epidermidis, and Klebsiellapneumoniae. Urine culture, urinalysis, and urinary Gram-stainshould be performed as part of sepsis evaluation for late-onsetneonatal sepsis, especially in male and preterm neonates

Etiological patterns of bacterial meningitis in neonatal sepsis Andy Setiawan; Idham Amir; Alan R. Tumbelaka
Paediatrica Indonesiana Vol 46 No 1 (2006): January 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi46.1.2006.32-6

Background Sepsis and meningitis are major causes of mortalityand morbidity in neonates. The prevalence of sepsis is around 1-4out of every 1000 live births, and one-fourth is accompanied bymeningitis. These numbers are higher in prematures.Objective To find out the prevalence and etiological patterns ofbacterial meningitis in neonatal sepsis, and the pattern of antibi-otic susceptibility for organisms causing bacterial meningitis.Methods This was a cross sectional study, conducted in the neo-natal ward and emergency room at Cipto Mangunkusumo Hospi-tal from October 2003 to October 2004.Results Seventy two neonates fulfilled the inclusion criteria andwere examined for blood and cerebrospinal fluid (CSF) cultures.Sixty out of 72 neonates were proven for sepsis. Bacterial menin-gitis was found in 18 neonates, and all cases were accompaniedby sepsis. Positive CSF cultures were found in 12 neonates. Theother six were diagnosed based on CSF cell count >32/Î¼l.Acinetobacter calcoaceticus was the major causative organismsin this study. The organisms were highly resistant to first line anti-biotics, except for chloramphenicol. They were also sensitive toceftazidime (second line), meropenem, and imipenem.Conclusions The prevalence of bacterial meningitis in neonatalsepsis at Cipto Mangunkusumo Hospital was 18/60 in 2003-2004.The major causative organism was Acinetobacter calcoaceticus.Antibiotic resistance was very high and only chloramphenicol,ceftazidime, meropenem, and imipenem remain effective

Co-Authors Alan R. Tumbelaka Alan Roland Tumbelaka Andy Setiawan Kemas Firman Maswin Masyhur Nia Kurniati Novie Amelia Partini P Trihono Sudigdo Sastroasmoro Sukman Tulus Putra Taralan Tambunan Vera M Manoe

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