The increasingly high cost claims for caesarean section cases in the National Health Insurance or Jaminan Kesehatan Nasional (JKN) era mean that hospitals are required to provide service efficiency, the BPJS Health payment system to hospitals is through the INACBG's (Indonesia Case Based Groups) rates. The purpose of this study is to analyze the influence of clinical pathway compliance and prescription writing according to the national formulary on cost control with caesarean section indication as an intervening variable at St Theresia Hospital. This type of research is confirmatory research using a quantitative approach. The sample in this study amounted to 80 samples from caesarean section cases in August-October 2023. The sampling technique used purposive sampling. Based on the results of testing the Path coefficients hypothesis, it was found that F count (63.047) > F Table (3.432) with a significance level of 0.05, the results of the t value> 1.96 and p < 0.05. The results of data analysis and hypothesis testing showed that there was an influence of clinical pathway compliance, writing prescriptions according to the national formulary and indications for caesarean section on cost control.