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All Journal The Indonesian Biomedical Journal ACI (Acta Cardiologia Indonesiana) Heart Science Journal Eureka Herba Indonesia
Ardian Rizal
Department Of Cardiology And Vascular Medicine, Faculty Of Medicine, Universitas Brawijaya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : ACI (Acta Cardiologia Indonesiana)

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Increasing Age, Diabetes Mellitus and Beta Blocker Influence Heart Rate Recovery Values in Patients Undergoing Exercise Treadmill Test Adriyawan Widya Nugraha; Cholid Tri Tjahjono; Ardian Rizal
ACI (Acta Cardiologia Indonesiana) Vol 5, No 1 (2019)
Publisher : Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (661.347 KB) | DOI: 10.22146/aci.44550

Abstract

Background: Heart disease is the number one cause of death globally. This disease is initiation affected by autonomic dysfunction which will cause disruption of the sympathetic-parasympathetic system. Heart Rate Recovery (HRR) is used to determineautonomic dysfunction.Objective: To determine the relationship of risk factors and cardiovascular treatment to HRR values of 1 minute and 2 minutes.Methods: Cross sectional study to measure HRR 1 and 2 minute undergoing exercise treadmill test for the screening of coronary heart disease in Saiful Anwar hospital in May 2016 until September 2017. Univariate analysis was performed to determine the frequency and proportion of HRR values classified into normal groups (HRR 1 minute > 12x / minute or HRR 2 minutes > 22x / minute) and abnormal groups (HRR 2 minutes ≤ 12x / minute or HRR 2 minutes ≤ 22x / minute).We also performed bivariate analysis using comparative test (Generalized Linear Model) and correlation test (Pearson, Spearman and Eta) and multivariate linear regression analysis.Results: This study found that age, hypertension and beta blocker were significantly associated with HRR abnormalities (p<0.05). HRR 1 and HRR 2 were significantly associated with diabetes mellitus (DM) (p=0.004 and p=0.039) and beta blocker (p=0.042 and p=0.039). Then looking at the relationship of multivariate correlations found a significant correlation between age (β=-0.133, p=0.000) and DM (β=-2.617, p=0.032) at 1 minute HRR and significant correlation with age (β=-0.165, p=0.004) and beta blockers (β=-2,947, p=0.017).Conclusion: increasing of age, diabetes mellitus and beta blockers correlate with decreasing of HRR. The most influential risk factors for HRR values of 1 minute were increasing age and DM, while for HRR values of 2 minutes were increasing age and beta blockers.
Co-Authors Achmad Guntur Hermawan Suryo Adji Adhika Prastya Wikananda Aditha Satria Maulana Adriyawan Widya Nugraha Al Mazida Fauzil Aishaqeena Aloysius Yuwono Suprapta Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Anna Fuji Rahimah Aris Munandar ZI Aris Munandar Zulkifli Ismail Budi Satrijo Budi Satrijo Bunga Bella Pratiwi Cholid Tri Tjahjono Cik Kahadi Dea Arie Kurniawan Diah Ivana Sari Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Djanggan Sargowo Estyka Ratu Fahmy Rusnanta Fahmy Rusnanta Fahriza Abid Sonia Fajar, Jonny Karunia Fandy Hazzy Alfata Faris Wahyu Nugroho Ferry Sandra Ferry Sandra Fitranti Suciati Laitupa Harris Kristanto Heny Martini Heny Martini Heny Martini Icmi Dian Rochmawati Indra Prasetya Indra Prasetya Intan Masyfufah Hanim Khilmi Ainun Nadliroh Mohammad Rizki Fadlan Mohammad Saifur Rohman Mohammad Saifur Rohman Mohammad Saifur Rohman Mohammad Saifur Rohman Muhamad Rizki Fadlan Muhammad Saifur Rohman Novi Kurnianingsih Novi Kurnianingsih Novi Kurnianingsih Novi Kurnianingsih Novi Kurnianingsih Novi Kurnianingsih Olivia Handayani Olivia Handayani Peter Sugita Puspa Lestari Putri Annisa Kamila Putri Annisa Kamila Rizkia Milladina Hidayatulloh Sasmojo Widito Sasmojo Widito Sasmojo Widito Sasmojo Widito Sasmojo Widito Sasmojo Widito Sasmojo Widito Seprian Widasmara Setyasih Anjarwani Setyasih Anjarwani Setyasih Anjarwani Sri Winarsih Susanti Lara Dewi Syanindita Puspa Wardhani Taufieq Ridlo Makhmud Tonny Adriyanto Valerinna Yogibuana Veny Kurniawati Wiwit Nurwidyaningtyas Yoga Waranugraha Yuke Fawziah Kemala