Urip Urip
Jurusan Analis Kesehatan, Politeknik Kesehatan Kementerian Kesehatan Mataram

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Journal : Bioscientist : Jurnal Ilmiah Biologi

Studi Jamur Aspergillus fumigatus di Pasar Cakranegara Kota Mataram Penyebab Penyakit Aspergillosis Menggunakan Media Pertumbuhan Potato Dextrose Agar Urip Urip; Yunan Jiwintarum; Ni Luh Putu Gita Gandi
Bioscientist : Jurnal Ilmiah Biologi Vol 9, No 2 (2021): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v9i2.4560

Abstract

This study aims to isolate, identify, and analyze the fungus Aspergillus fumigatus that causes aspergillosis in Cakranegara Market, Mataram City using Potato Dextrose Agar (PDA) growth media. This research method uses descriptive observation, with Non-Random Purposive Sampling technique. The research sample amounted to 15 consisting of 3 types, namely: air, vegetables, and food (market snacks). Each sample was prepared and then isolated using PDA media and incubated for 3 x 24 hours at 37ÂșC, then identified and analyzed to find the fungus Aspergillus fumigatus in each of these samples. Based on the research that has been done, the results obtained from 15 samples, namely 9 positive samples (+) found Aspergillus fumigatus and 6 negative samples (-) Aspergillus fumigatus was found. Details of the percentages in each sample, namely: in the air sample, 4 of 5 samples (80%) were positive for Aspergillus fumigatus, in the vegetable sample, 3 out of 5 samples (60%) were positive for Aspergillus fumigatus, and in the food sample, 2 were obtained. of 5 samples (40%) positive found Aspergillus fumigatus. The highest percentage of Aspergillus fumigatus was found in air samples, which is a direct contact that causes aspergillosis. The percentage of the total sample found by Aspergillus fumigatus was 60%.
Pengaruh Variasi Masa Pengobatan Obat Anti Tuberkulosis (OAT) terhadap Billirubin dalam Urine Penderita Tuberkulosis Metode Carik Celup Riska Novitasari; Urip Urip; Erlin Yustin Tatontos; Aurira Thrisna Dwi Aprianti
Bioscientist : Jurnal Ilmiah Biologi Vol 10, No 1 (2022): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v10i1.5668

Abstract

Treatment of Tuberculosis using Anti Tuberculosis Drugs (OAT) has a hepatotoxic effect that can cause liver function disorders, one of which is bilirubin. Examination of bilirubin can use blood and urine. Qualitative and semi-quantitative examination of bilirubin in urine by diazo reaction using the dipstick or dipstick method is widely used because it is fast, more practical, and more sensitive. The purpose of this study was to determine the effect of variations in the treatment period of Anti Tuberculosis Drugs (OAT) on bilirubin in the urine of tuberculosis patients. This research is an analytical observational research. The sample in this study amounted to 20 people in the initial and follow-up treatment periods. Urine samples in patients with tuberculosis were examined for urine bilirubin levels using the dipstick method. The results showed that the level of bilirubin in the urine qualitatively in the early stages of treatment had a positive value, namely 5 out of 9 tuberculosis patients (56%) with a positive level of 1 (+1) semi-quantitatively. The level of bilirubin in the urine qualitatively in the advanced stage of treatment has a positive value, namely 1 out of 11 tuberculosis patients (9%) with a positive level of 1 (+1) semi-quantitatively. The results of the Chi-Square bilirubin test in urine qualitatively and semi-quantitatively showed the value of p = 0.024 < = 0.05. The conclusion is that variations in the treatment period of Anti Tuberculosis Drugs (OAT) have an effect on bilirubin in the urine of tuberculosis patients.