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All Journal MEDIA MEDIKA INDONESIANA International Journal of Science and Engineering (IJSE) Jurnal Kesehatan Andalas Jurnal Berita Ilmu Keperawatan Jurnal Keperawatan Padjadjaran Inovasi : Jurnal Ekonomi, Keuangan, dan Manajemen Journal Of Holistic Nursing Science Jurnal Kreativitas PKM Journal of Tropical Pharmacy and Chemistry Kumawula: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmu Kesehatan Jurnal Kebidanan Mutiara Mahakam Jurnal Sains dan Kesehatan Jurnal Medika: Karya Ilmiah Kesehatan TRIAGE MOTORIK Prosiding Seminar Nasional Unimus

Endang Sawitri

Fakultas Kedokteran Universitas Mulawarman

Author-ID : 374822

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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GAMBARAN MORTALITAS PASIEN DI RUANG PICU RSUD ABDUL WAHAB SJAHRANIE SAMARINDA PERIODE 2016-2017 Hajari, Siti; Sawitri, Endang; Muhyi, Annisa; Nugroho, Hary
Jurnal Kebidanan Mutiara Mahakam Vol 7 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan Mutiara Mahakam

Pediatric Intensive Care Unit (PICU) is a spscial functional caring unit thatprovides intensive treatments for infants and children. Human resources in PICU will doanything they can to save patients. This research try to describe the mortality patients inthe PICU room of RSUD Abdul Wahab Sjahranie Samarinda in the 2016-2017 period.We plan to use observational descriptive study using cross sectional data from medicalrecords of 2016-2017 PICU patients who had fulfilled the inclusion criteria of 143samples. The results showed that patients died at the age of <60 months (49.3%) and â‰¥60months (18.1%), male sex died as much (34.4%) and (32.9%) in women , the diagnosiswas pneumonia (27.3%), GIT abnormalities (19.6%) and encephalitis (8.4%). Durationof treatment for <48 hours (25.2%), 48-120 hours (26.6%) and> 120 hours (48.3%), thenled to death caused were respiratory failure (48.2%), septic shock ( 21.7%) and multiorganfailure (10.5%). The majority of patients who died in PICU within <60 months,men, diagnosis of pneumonia, length of treatment> 120 hours with the most commoncause was respiratory failure.

PENGARUH PEMBERIAN INFORMASI PRA BEDAH TERHADAP TINGKAT KECEMASAN PADA PASIEN PRA BEDAH MAYOR DI BANGSAL ORTHOPEDI RSUI KUSTATI SURAKARTA Sawitri, Endang; Sudaryanto, Agus
Jurnal Berita Ilmu Keperawatan Vol. 1, No 1, 2008
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bik.v1i1.131

The background of this research is the invention of particular phenomena, which the patient is on anxiety feeling at pre surgery stage, particularly the femur fracture patient on the orthopedic ward RSUI Kustati Surakarta. While, the aim of this study is to find the influence of delivering information pre surgery through the rate of decreasing patient anxiety before surgery. This research is planed as the experimental research at the type of one group pre test â€“ posttest, completed with 58 subject. The sample collecting technique is at the same time with the method of quota sampling, while, the method of collecting data is completed with the questioner which is contain of the measurement of anxiety as Hamilton Anxiety Scale. The data analysis technique is using t-test. The result of the research is shows that there is differences of the rate of anxiety on the patient, before and after the therapeutic communication: the delivering information pre surgery at the orthopedic ward RSUI Kustati Surakarta. At least, it is shown with the computed of hiphotesys test completed with the significance rate as 5 % and the free degree of 57, it is shows that the result of t computed = 7,366 ttable = 2,002. However, related through the result of the research, it is suggested that the delivering information of pre surgery at the orthopedic ward RSUI Kustati Surakarta is extremely needed to be increased, at least, it is to descend the rate of patient anxiety in having surgery

Hubungan Lama Penggunaan Kontrasepsi Hormonal Dengan Gejala Klimakterik Pada Wanita Usia Menopause di Desa Gumul Sari, Devi Permata; Sawitri, Endang; Putri, Zeni Evilya
Journal of Holistic Nursing Science Vol 8 No 1 (2021): (JANUARY)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/nursing.v8i1.3938

The aging process in women will occur a phases of climacteric, which causes the various of climacteric symptoms. One of the treatments to overcoming climacteric symptoms is using hormone replacement therapy. Hormonal contraception can be used to replace the estrogen and progesterone hormones, it also relieve a clinical estrogen deficiency complaints. However, long term of using hormonal contraceptive can increase the climacteric symptoms. The purpose of this research is to find out the relationship between duration of hormonal contraception use with climacteric symptoms in menopausal women in gumul village. This research is descriptive correlational type with cross sectional approach. The population in this research is menopausal women which is 44-55 years old in Gumul village, amount of 228 people. Respondents of the research is amount of 70 people were obtained using non probability technique sampling with type of purposive sampling. The data collecting instrument is using Google form which contains a demographic data and menopause rating scale. The research result using kendalâ€™s tau test statistic obtained p value = 0,00 (p value < 0,05) meaning there is relationship between duration of hormonal contraception use with climacteric symptoms in menopausal women. Correlation coefficient value or r = 0,902 shows a very strong positive correlation, means that duration of hormonal contraception use can increase the climacteric symptoms

The Effect of Aerobic Exercise on Blood Glucose Level among Patients with Type-2 Diabetes Mellitus Yasmiin Khoirul Bariyyah; Endang Sawitri; Rahmat Bakhtiar
Jurnal Ilmu Kesehatan Vol 9 No 2 (2021): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v9i2.2256

Abstract: Diabetes Mellitus is the disease which causes premature mortality, and the leading cause of blindness, heart disease, and kidney failure in the world with increasing prevalance. Exercise is fundamental in Diabetes Mellitus management which functions to improve insulin sensitivity and control blood glucose level. A number of studies have been carried out to explore the effect of aerobic exercises on blood glucose level among patients with type-2 Diabetes Mellitus. The research aimed to evaluate the effect of aerobic exercise’s type, frequency, intensity and duration on blood glucose level among patients with type-2 Diabetes Mellitus. This study was systematic review. The literature searches were specified from 2005-2020 through Pubmed and Google Scholar. 40 studies in total based on specific criteria was included to this study. Thirty-nine out of forty studies revealed that a variety of aerobic exercises such as walking, gymnastic (diabetic, aerobic, foot, ergonomic), step test as well as static cycling give impact on lowering blood glucose level. Seventeen out of forty studies fulfilling the criteria of frequency, duration and intensity showed that exercise helps reduce blood glucose level. In conclusion, performing aerobic exercise regularly and appropriately helps to lower blood glucose level among patients with type-2 Diabetes Mellitus.

Pengaruh Pemberian Ekstrak Phyllanthus niruri Linn Terhadap Infiltrasi Limfosit dan Ekspresi Perforin pada Kanker Kolon Tikus Sprague-Dawley Endang Sawitri; Ign. Riwanto; Tjahjono Tjahjono; Edi Dharmana
MEDIA MEDIKA INDONESIANA 2013:MMI VOLUME 47 ISSUE 1 YEAR 2013
Publisher : MEDIA MEDIKA INDONESIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.732 KB)

ABSTRACTThe effect of Phyllanthus niruri Linn extract on lymphocytes infiltration and perforin expression in colon cancer of Sprague-Dawley RatBackground: Colon cancer treatment currently involves immunotherapy that aims to improve the quality of life and survival of patients. Phyllanthus niruri Linn (P. niruri L) may act as an immunomodulator, but its potency in antitumor immune responses has not been revealed. The study was conducted to evaluate the differences between the immunological status of rats suffering colon cancer which were not given to those given the extract of P. niruri L.Methods: The study was randomized posttest-only control group design. Samples were 30 Sprague-Dawley male rats, bodyweight 170-220 gr which induced by 1.2 DMH 30 mg/kgBW subcutaneously. On the weeks 9, 11 and 13, four induced rats each week were sacrified to detect the development of colon cancer. On the weeks of 13th all of 4 rats were developed colon cancer, so the induction were stopped. The rest of 18 induced rats were randomly into two groups: without P. niruri L or positive control (K+)=9 rats and given P. niruri L extract 13.5 mg/kg orally or X group=9 rats. After 19th week all of rats were then terminated and tumor lesion of colon were processed hystophatologically. The tissues of colon cancer were stained by H&E for evaluate the lymphocytes infiltration and immunohistochemistry monoclonal antibody anti-perforin for perforin expression. Non pairs t-test was used with considered significant if p<0.05.Results: The mean of lymphocytes infiltration of the group X was 401.89±70.19, it was higher compared to K+ 191.89±50.68 (p=0.000). The mean percentage of perforin expression of group X was 39.00±1.80%, it was higher compared to K+ 23.00± 3.00% (p=0.000). Conclusion: The extract of P. niruri L increases immunologic status through mechanism of lymphocytes infiltration and perforin expression elevation of colon cancer in animal mode.Keywords : Phyllanthus niruri Linn, colon cancer, lymphocytes infiltration, perforinABSTRAKLatar belakang: Penanganan kanker kolon saat ini melibatkan imunoterapi yang bertujuan untuk meningkatkan kualitas hidup dan survival penderitanya. Phyllanthus niruri Linn bekerja sebagai imunomodulator, tetapi potensinya dalam respons imun antitumor belum banyak diungkap. Penelitian bertujuan untuk mengevaluasi perbedaan status imunologis antara tikus coba yang menderita kanker kolon yang tidak diberi dengan yang diberi ekstrak P. niruri L.Metode: Penelitian ini merupakan randomized posttest-only control group design. Sampel berupa 30 ekor tikus Sprague-Dawley jantan, yang diinduksi 1,2 DMH 30 mg/kgBB subkutan sekali setiap minggu. Pada minggu ke-9, 11 dan 13 masing-masing empat ekor tikus dimatikan untuk melihat perkembangan tumor. Minggu ke-13 pada kolon empat tikus telah tumbuh kanker kolon, sehingga induksi dihentikan dan sisa 18 tikus dirandom alokasi menjadi 2 kelompok. Kelompok kontrol positif (K+) tanpa pemberian P. niruri L (9 tikus) dan kelompok diberi P. niruri L. 13,5 mg/kg per hari melalui sonde (9 tikus). Minggu ke-19 semua tikus diterminasi, lesi tumor pada kolon diproses menjadi sediaan histopatologik, kemudian dipulas dengan H&E untuk memeriksa infiltrasi limfosit dan pulasan imunohistokimia menggunakan antibodi monoklonal anti-perforin untuk melihat ekspresi perforin. Analisis data menggunakan uji t tidak berpasangan dengan derajat signifikansi p<0,05.Hasil: Rerata jumlah infiltrasi limfosit kelompok X adalah 401,89±70,19 lebih tinggi dibanding kelompok K+ yaitu191,89±50,68 (p=0,000). Persentase rerata ekspresi perforin kelompok X sebesar 39,00±1,80%, lebih tinggi dibandingkan dengan K+ yakni 23,00±3,00% (p=0,000).Simpulan: Ekstrak P. niruri L meningkatkan status imunologi melalui mekanisme peningkatan infiltrasi limfosit dan ekspresi perforin untuk melawan kanker kolon pada tikus coba

Ekstrak Phyllanthus niruri Linn, Pertumbuhan Tumor dan Proliferasi Sel Kanker Kolorektal: Studi Eksperimental pada Tikus Sprague-Dawley yang Diinduksi 1,2 DMH Endang Sawitri; Ign. Riwanto; Tjahjono Tjahjono; Edi Dharmana
MEDIA MEDIKA INDONESIANA 2012:MMI VOLUME 46 ISSUE 1 YEAR 2012
Publisher : MEDIA MEDIKA INDONESIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.603 KB)

Effect of Phyllanthus niruri Linn extract on tumor growth and cell proliferation of colorectal cancer: experimental study in 1.2 DMH-induced Sprague-Dawley ratsBackground: The development of chemotherapy for colorectal cancer (CRC) is so very advanced, however, the survival of patients has not been satisfactory, therefore, the current therapy also involve immunotherapy. Phyllanthus niruri Linn (P. niruri L) may act as an immunomodulator and anticancer, but its potency has not been revealed. Study was conducted to confirm the effects of P. niruri L extract in the treatment of CRC.Method: The study was randomized posttest-only control group design. Samples were Sprague-Dawley male rats, bodyweight 170- 220 gr, were divided into two groups: non induced or negative control (K-) consisted of 9 normal rats, and induced by 1.2 DMH 30 mg/kgBW subcutaneously group consisted 30 rats. On the weeks 9, 11 and 13, four induced rats each week were sacrified to detect the development of CRC. On the weeks of 13th all of 4 rats were developed CRC, so the induction were stopped. The rest of 18 induced rats were randomly into two groups: without P. niruri L or positive control (K+)=9 rats and given P. niruri L extract 13.5 mg/kg orally or X group=9 rats. After 19th week all of rats were then terminated and tumor lesion of colon were examined macroscopically and hystophatologic tissues were stained with AgNORs for evaluate the cells proliferation. Oneway Anova and Post Hoc LSD test for the growth of colon tumor and non pairs t-test for cell proliferation were used. Considered significant if p was <0.05. Result: There was no tumor growth on K- group, while for K+ was 83.33±14.34% and on X was 40.44±13.23% (p=0.000). The mean of AgNORs on K+ was 4.60±0.55 while on X was 2.25±0.39 (p=0.000).Conclusion: The extract of P. niruri L suppress the tumor growth and cell proliferation of CRC.Keywords: Phyllanthus niruri Linn, colorectal cancer, tumor growth, proliferationABSTRAKLatar belakang: Perkembangan kemoterapi untuk kanker kolorektal (KKR) sangat maju, tetapi kelangsungan hidup penderitanya belum memuaskan, sehingga penanganan multimodalitas juga melibatkan imunoterapi yang bertujuan untuk meningkatkan kualitas hidup. Phyllanthus niruri Linn dapat bekerja sebagai imunomodulator sekaligus antikanker, tetapi potensinya belum banyak diungkap. Penelitian bertujuan untuk menganalisis pengaruh pemberian ekstrak P. niruri L terhadap pertumbuhan tumor danproliferasi sel KKR.Metode: Penelitian ini merupakan randomized posttest-only control group design. Sampel berupa tikus Sprague-Dawley jantan, dibagi 2: kelompok tanpa induksi 1,2 DMH dan tanpa P. niruri L (K-: kelompok kontrol negatif) sebanyak 9 ekor dan kelompok induksi 1,2 DMH 30 mg/kgBB subkutan setiap minggu sebanyak 30 ekor. Pada minggu ke-9, 11 dan 13 masing-masing empat ekor tikus dibunuh untuk melihat perkembangan tumor. Pada minggu ke-13 keempat tikus telah berkembang menjadi KKR, induksidihentikan dan sisa 18 tikus dirandom alokasi menjadi 2 kelompok. Kelompok kontrol positif (K+) tanpa pemberian P. niruri L (9 tikus) dan kelompok diberi P. niruri L. 13.5 mg/kg per hari melalui sonde (9 tikus). Minggu ke-19 semua tikus diterminasi, diperiksa lesi tumor makroskopik pada kolon. Jaringan histopatologik diwarnai AgNORs untuk memeriksa proliferasi sel. Analisis data meliputi analisis deskriptif dan uji Oneway Anova, dilanjutkan dengan post hoc test LSD untuk pertumbuhan tumor kolon dan uji ttidak berpasangan untuk proliferasi sel. Derajat signifikansi yang dipilih adalah p<0,05. Hasil: Tidak ditemukan pertumbuhan tumor pada kelompok K-. Persentase rerata pertumbuhan tumor kelompok X sebesar40,44±13,23%berbeda sangat signifikan (p=0,000) dibanding K+ sebesar 33±14,34%. Rerata bercak AgNORs kelompok K+sebesar 4,60±0,55 dan menurun pada kelompok X (2,25±0,39), terdapat perbedaan yang sangat signifikan pada kedua kelompok (p=0,000). Simpulan: Ekstrak P. niruri L menekan pertumbuhan tumor dan proliferasi sel kanker kolorektal.

Apoptosis of Colorectal Cancer Cell on Sprague-Dawley Rats Induced with 1,2 Dimethylhidrazine and Phyllanthus niruri Linn Extrac Endang Sawitri
International Journal of Science and Engineering Vol 10, No 1 (2016)
Publisher : Chemical Engineering Diponegoro University

Apoptosis cell is one of the main biomolecular predictors to determine kind of treatment given to patient with colorectal cancer and to predict the end result. Phyllanthus niruri Linn (P. niruri L) acts as antineoplastic but its potency on the process of cancer cell apoptosis has not been revealed yet. The objective of the research was to evaluate the apoptosis index of rats with colorectal cancer treated with and without P. niruri L. extract. This research used The Randomized Posttest-Only Control Group Design. As many as 30 male Sprague-Dawley rats were induced with 1,2 DMH 30 mg/kgBW once in every week. Four rats were sacrificed at week 9th, 11th and 13th to be observed the development of colorectal cancer. Induction was then stopped and other 18 rats were randomly located into two groups. The first group was positive control (K+) group consisted of 9 rats without P. niruri extract. The second group (X) was consisted of 9 rats with the application of P.niruri L. extract 13.5 mg/kg per day orally. All rats were terminated on week 19th, tumor lesion was proceed for Histopathology preparations and stained with Kit TUNEL-IHC (Apo-BrdU-IHCTM BioVision Cat #K403) to identify the apoptosis cell. Data were analyzed using unpaired t-test with significant level of p<0.05. The result showed that the average of apoptosis index of X treatment was 2.37 + 0.48 higher than K+ treatment namely 1.45 + 0.41 with a highly significance difference (p=0.000). Phyllanthus niruri L extract increased the apoptosis of colorectal cancer of Sprague-Dawley rats induced with 1,2 Dimethylhidrazine

Analysis The Student Perception of Application Clinical Skills Online Learning in The Pandemic Time Covid-19 Anik Puji Rahayu; Sulistiyawati Sulistiyawati; Cicih Bhakti Purnamasari; Endang Sawitri; Ika Fikriah
Jurnal Keperawatan Padjadjaran Vol. 9 No. 2 (2021): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v9i2.1600

Background: Government policies that apply social distancing, work from home, and learn from home to prevent the spread of the Covid-19 corona virus have an impact on learning methods. Clinical learning methods in pre-pandemic health education are carried out in campus laboratories and direct clinical services to patients. Thus, in this condition, the provision cannot be implemented. Purpose: For this reason, it is necessary to modify the learning method from offline to online to meet the continuity of the student learning process. Methods: In the first stage, the clinical skills online learning method using online videos is supported by lecturers’ explanations in a 120-minute meeting. In the second stage, students are given the task of making videos of procedural skills that have been taught in 170 minutes, with a video duration of 10-15 minutes. At the next meeting, a review or response is carried out with students on the standard operating procedure and the theory that underlies it. The design in this study is a descriptive analysis with 511 respondents from the medical education study program and the nursing diploma 3 study program at the Faculty of Medicine, Mulawarman University. The research used was 44 items of statement questionnaire that had been tested for validity and reliability, and questionnaire items were sent to respondents via Google Forms. Results: From the results of this study, there is a significant relationship between the perceptions of students who apply clinical skills online learning seen from the effectiveness of learning in the Covid-19 pandemic era with p-value = 0.000, with a very strong relationship with the Spearman value rho of 0.791 in a positive direction. Conclusion: Thus, it can be concluded that the application of online clinical skills learning during the Covid-19 pandemic was effective. As a suggestion, clinical learning methods with various blended learning or hybrid learning methods should be modified.

Pemberian Suplemen Jahe Merah Dan Senam Kaki Diabetik Bagi Jamaah Masjid Alam Semesta (MAS) Sempaja Samarinda Mayusef Sukmana; Ida Ayu Kade Sri Widiastuti; Endang Sawitri; Nurul Hasanah; Muhammad Aminuddin; Iwan Samsugito; Anik Puji Rahayu; Azi Surya Kurniawan; Yoga Bowo Leksono; Syaiful Yanwar
JURNAL KREATIVITAS PENGABDIAN KEPADA MASYARAKAT (PKM) Volume 4 Nomor 5 Oktober 2021
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v4i5.4310

ABSTRAK Pelaksanaan kegiatan ibadah di masjid memiliki risiko terjadinya penularan covid-19. Upaya yang dilakukan mencegah penularan selain menerapkan protokol kesehatan adalah dengan meningkatkan imunitas dan meningkatkan kebugaran jamaah masjid melalui pemberian jahe dan senam kaki diabetic. Pengabdian masyarakat bertujuan jamaah masjid Alam Semesta Sempaja Samarinda mampu mempraktikan senam kaki diabetik dan meminum jahe dalam rangka meningkatkan kebugaran dan imunitas tubuh. Metode yang digunakan adalah mendemontrasikan senam kaki diabetic, senam bersama, edukasi manfaat jahe, meminum jahe bersama dan membagikan jahe untuk 7 hari. Kegiatan menerapkan protokol kesehatan melalui pengukuran suhu dan membagikan masker, Kegiatan dikuti oleh seluruh jamaah Masjid Alam Semesta Sempaja berjumlah 80 orang. Para jamaah mampu melakukan senam kaki diabetic dan rutin meminum jahe. Kata kunci : Senam Kaki Diabetic, Jahe ABSTRACT The implementation of worship activities in mosques has a risk of covid-19 transmission. Efforts made to prevent transmission in addition to implementing health protocols are to increase immunity and improve the fitness of mosque’s congregations through the provision of ginger water and diabetic foot exercises. Community service aims at the congregation of the Alam Semesta Sempaja Samarinda mosque to be able to practice diabetic foot exercises and drink ginger water in order to improve fitness and immunity. The method used was to demonstrate diabetic foot exercise, doing the exercise together, educate the benefits of ginger water, drink ginger water together and distribute ginger water for 7 days. The activity of implementing health protocols by measuring temperature and distributing masks, this activity was attended by 80 congregations of the Alam Semesta Sempaja Mosque. The congregation is able to do diabetic foot exercises and drink ginger water regularly. Keyword: Diabetic Foot Gymnastics, Ginger Water

Effect of Ethanol Extract of Eleutherine bulbosa (Mill.) URB on Anaerobic Bacterial Prophyromonas gingivalis In Vitro Siti Nur Azizah; Sinar Yani; Sjarif Ismail; Masyudhi Masyudhi; Endang Sawitri
Journal of Tropical Pharmacy and Chemistry Vol. 4 No. 3 (2018): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Periodontitis is an inflamation of supporting tissues on teeth that became the main cause of Prophyromonas gingivalis (P. gingivalis) bacteria. Treatment of periodontitis is by giving antibacterial agent therapy. Plants that have antibacterial effects one are Eleutherine bulbosa (UEB) bulbs from the Iridaceae family. This plant has been used for ethnobotany boils drugs and has been known to have antibacterial activity toward against intestinal pathogen bacteria that is anaerobic Gram Negative, but still unknown its activity against on oral pathogenic bacteria such as P. gingivalis. The purpose of this study was to know the effect of UEB extract on the growth of P. gingivalis bacteria as in vitro. UEB is taken from agriculture center in Samarinda city. UEB Simplisia was tested for antibacterial activity using Kirby-Bauer disc diffusion method on BHI-A media supplemented with vitamin K and hemin. The bacteria which used were P. gingivalis ATCCÂ® 33277. Blank disc 6 mm with nine concentrations attached to BHI-A medium, incubated for 24 hours at 37 Â°C in an anaerobic atmosphere, then sprayed MTT (3-[4,5-Dimethylthiazole-2-yl]-2,5-diphenylttetrazoliumbromide) reagent and read a few moments later. For comparison, then used Chlorhexidine gluconate (CHX) 2 mg/ml. The statistical analysis with t-test and there was significant different if p<0.05. The result showed that the higher concentration of UEB ethanol extract will increase the growth inhibition zone of P. gingivalis bacteria and reach maximum at 10 mg/ml concentration. The result of t-test showed no difference significant of P. gingivalis bacterial inhibition zone in the treatment group of 7.5 mg/ml and 10 mg/ml concentration on CHX group. This study proves UEB ethanol extract can inhibit the growth of P. gingivalis bacteria.

Co-Authors - Setianingsih Agus Sudaryanto Agustina Rahayu Magdaleni Agustina Rahayu Magdaleni Ahmad Fikri Akbar Anik Puji Rahayu Annin Dya Maina Annisa Muhyi Apriani T Arie Ibrahim Azi Surya Kurniawan Boyke Rorimpandey Boyke Soebhali Cicih Bhakti Purnamasari Devi Permata Sari Edi Dharmana Edi Dharmana Enggarita Widyahapsari Erwin Ginting Esmaya R. A. Adaniyah Evi Fitriany Fikriah, Ika Hajari, Siti Hamdi Mayulu Hary Nugroho Hary Nugroho Ida Ayu Kade Sri Widiastuti Ign. Riwanto Ign. Riwanto Ilham Akbar Choirul Umam Indra Sukmana Putra Indri Septiana Irawiraman, Hadi Irsan Tricahyadinata Iwan Samsugito Masyudhi Masyudhi Moriko Pratiningrum Muhammad Aminudin Muhammad Fachrian Akbar Muhammad Rezwan Qhuzairi Nur Khoma Fatmawati Nurul Fadhila Lestari Nurul Hasanah Nurul Hasanah Poppy Desra S Nasution Putri, Zeni Evilya Rahmat Bakhtiar Rahmat Bakhtiar Regina Anastasia Sanjaya Rizky Setya Tama Rochimah Thul Ulyah Rudi Saputra Setianingsih Setianingsih Silfia Purnawati Sinar Yani Siti Khotimah Siti Nur Azizah Sjarif Ismail Sofia Apriyanti Sulistiawati Sudarso Sulistiawati Sulistiawati Sulistiyawati Sulistiyawati Syaiful Yanwar Syifa Fitria Anggraeny Taufan Purwokusumaning Daru Tjahjono Tjahjono Tjahjono Tjahjono Yasmiin Khoirul Bariyyah Yoga Bowo Leksono

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