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UNCONTROLLED TYPE 1 DIABETES MELLITUS WITH TUBERCULOMA IN INFERIOR LOBE LEFT LUNG AND BILATERAL HYDRONEPHROSIS IN CHILD Wardhana, Anggia Rarasati; Sukartini, Sukartini; Muhyi, Annisa
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1155

Diabetes Mellitus (DM) is an important risk factor for the development of active tuberculosis (TB). It is chronic and will weaken the immune system causing the patient have increased risk of tuberculosis by three-fold.We present a case of 13-year-old girl with chest pain and cough. She has a previous history of type 1 DM. Laboratory findings showed hyperglycemic state. Thoracic CT showed tuberculoma of inferoposterior lobe left lung, while abdominal CT showed bilateral hydronephrosis. He was then administered TB treatment of 2HRZE/10RH, corticosteroid, and insulin regiments with strict monitoring of blood glucoses. Clinical symptoms and blood glucose level were significantly improved after treatment.

GAMBARAN MORTALITAS PASIEN DI RUANG PICU RSUD ABDUL WAHAB SJAHRANIE SAMARINDA PERIODE 2016-2017 Hajari, Siti; Sawitri, Endang; Muhyi, Annisa; Nugroho, Hary
Jurnal Kebidanan Mutiara Mahakam Vol 7 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan Mutiara Mahakam

Pediatric Intensive Care Unit (PICU) is a spscial functional caring unit thatprovides intensive treatments for infants and children. Human resources in PICU will doanything they can to save patients. This research try to describe the mortality patients inthe PICU room of RSUD Abdul Wahab Sjahranie Samarinda in the 2016-2017 period.We plan to use observational descriptive study using cross sectional data from medicalrecords of 2016-2017 PICU patients who had fulfilled the inclusion criteria of 143samples. The results showed that patients died at the age of <60 months (49.3%) and â‰¥60months (18.1%), male sex died as much (34.4%) and (32.9%) in women , the diagnosiswas pneumonia (27.3%), GIT abnormalities (19.6%) and encephalitis (8.4%). Durationof treatment for <48 hours (25.2%), 48-120 hours (26.6%) and> 120 hours (48.3%), thenled to death caused were respiratory failure (48.2%), septic shock ( 21.7%) and multiorganfailure (10.5%). The majority of patients who died in PICU within <60 months,men, diagnosis of pneumonia, length of treatment> 120 hours with the most commoncause was respiratory failure.

Efek Pemberian Imunoterapi, Probiotik, Nigella sativa terhadap Th17, Neutrofil, dan Skoring Asma Muhyi, Annisa; Barlianto, Wisnu; Kusuma, HMS Chandra
Jurnal Kedokteran Brawijaya Vol 28, No 4 (2015)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Peran Th17 dalam patogenesis asma dan imunoterapi menjadi konsep dan paradigma terbaru. Imunoterapi merupakan salah satu manajemen di dalam asma dan memerlukan waktu yang lama sehingga sering mengakibatkan kegagalan terapi. Terapi adjuvant antara lain probiotik dan Nigella sativa diduga dapat meningkatkan efektifitas imunoterapi. Penelitian dilakukan untuk mengevaluasi efek pemberian imunoterapi, probiotik dan/atau Nigella sativa terhadap jumlah sel Th17, neutrofil dan skoring asma pada anak asma selama imunoterapi fase rumatan. Penelitian dilakukan pada Â 31 anak yang dikelompokkan secara acak yaitu imunoterapi plus plasebo atau imunoterapi plus Nigella sativa atau imunoterapi plus probiotik atau imunoterapi plus Nigella sativa plus probiotik selama 56 minggu. Pengukuran jumlah sel Th17 dan neutrofil dilakukan menggunakan flowsitometri setelah perlakuan. Asthma Control Test dilakukan untuk mengevaluasi gejala klinis. Data dianalisis menggunakan uji komparasi Anova One Way dan Â uji korelasi Pearson. Hasil menunjukkan tidak didapatkan perbedaan yang bermakna jumlah sel Th17 dan neutrophil antara kelompok perlakuan (p-value 0,199 dan 0,326). Asthma control test secara bermakna didapatkan perbedaan antara perlakuan imunoterapi plus probiotik dibandingkan imunoterapi saja. Skoring asma pada kelompok perlakuan imunoterapi plus probiotik adalah yang tertinggi (22,6). Jumlah sel Th17, neutrofil dan ACT menunjukkan hubungan yang lemah dan tidak bermakna secara statistik (r=-0,2) (p= 0,156). Jumlah sel Th17 dan neutrofil tidak didapatkan perbedaan yang bermakna. Skoring asma pada kelompok imunoterapi plus probiotik adalah yang tertinggi. Dapat disimpulkan tidak terdapat hubungan antara Th17, neutrofil dan skoring asma.Kata Kunci: Imunoterapi, neutrofil, Nigella sativa, probiotik, sel Th17, skoring asma

UNCONTROLLED TYPE 1 DIABETES MELLITUS WITH TUBERCULOMA IN INFERIOR LOBE LEFT LUNG AND BILATERAL HYDRONEPHROSIS IN CHILD Anggia Rarasati Wardhana; Sukartini Sukartini; Annisa Muhyi
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1155

Diabetes Mellitus (DM) is an important risk factor for the development of active tuberculosis (TB). It is chronic and will weaken the immune system causing the patient have increased risk of tuberculosis by three-fold.We present a case of 13-year-old girl with chest pain and cough. She has a previous history of type 1 DM. Laboratory findings showed hyperglycemic state. Thoracic CT showed tuberculoma of inferoposterior lobe left lung, while abdominal CT showed bilateral hydronephrosis. He was then administered TB treatment of 2HRZE/10RH, corticosteroid, and insulin regiments with strict monitoring of blood glucoses. Clinical symptoms and blood glucose level were significantly improved after treatment.

Hubungan Kadar Hemoglobin dengan Kejang Demam pada Anak yang Disebabkan Infeksi Saluran Pernapasan Akut: Studi Kasus Kontrol Amalia Aswin; Annisa Muhyi; Nurul Hasanah
Sari Pediatri Vol 20, No 5 (2019)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Latar belakang. Kejang demam adalah bangkitan kejang yang terjadi pada anak berusia 6 bulan sampai 5 tahun tanpa disebabkan oleh proses intrakranial. Kejang demam merupakan kelainan neurologi tersering yang dijumpai pada anak.Tujuan. Untuk mengetahui hubungan kadar hemoglobin dengan kejang demam pada anak yang disebabkan ISPA.Metode. Penelitian analitik observasional dengan desain kasus kontrol. Data diambil dari rekam medik di RSUD Abdul Wahab Sjahranie Samarinda tahun 2016-2017 menggunakan teknik purposive sampling. Variabel bebas adalah kadar hemoglobin, sedangkan variabel tergantung adalah kejang demam yang disebabkan ISPA. Analisis statistik menggunakan uji t tidak berpasangan dan chi-square (x2), kemaknaan ditentukan berdasarkan nilai p<0,05. Hasil. Didapatkan sebanyak 62 pasien dengan rincian 31 kejang demam dan 31 demam tanpa kejang. Prevalensi kejang demam pada anak laki-laki 71%, sedangkan perempuan 29%. Angka kejadian terbanyak kejang demam adalah usia 0-12 bulan dan gizi baik. Berdasarkan analisis data menggunakan uji t tidak berpasangan didapatkan rata-rata kadar hemoglobin pada kejang demam adalah 11,04 g/dL dan demam tanpa kejang 11,6 g/dL (p=0,023). Pada uji chi-square (x2), menunjukkan terdapat hubungan yang bermakna antara kadar hemoglobin dengan kejang demam yang disebabkan ISPA (p=0,032, OR=3,906)Kesimpulan. Terdapat hubungan kadar hemoglobin dengan kejang demam pada anak yang disebabkan ISPA.

Correlation between leukocyte count and hemoglobin with the incidence of febrile seizures at RSUD Abdul Wahab Sjahranie Samarinda Muhammad Harbiyan Acikdin; Annisa Muhyi; Vera Madonna Lumban Toruan
Pediatric Sciences Journal Vol. 3 No. 1 (2022): (Available online 1 June 2022)
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v3i1.31

Background: Febrile seizures occur at the age of 6 months to 5 years, ranging from 2-5% of cases in children. The sign when the body is fighting infection is the process that occurs, the presence of infection in the body causes a change in the leukocyte count, and high fever can trigger a decrease in hemoglobin. This study aims to determine the relationship between leukocytes and hemoglobin with the incidence of febrile seizures in children. Methods: This research is analytic observational with a cross-sectional design. The research data was taken from medical records at Abdul Wahab Sjahranie Hospital Samarinda with a purposive sampling method. The study sample was children aged 6 months to 5 years who had febrile seizures and fever without seizures and met the inclusion and exclusion criteria. Statistical analysis of this study used the chi-square test. Results: The chi-square test results were obtained on hemoglobin and leukocyte count with the incidence of febrile seizures with a p-value on the number of leukocytes (p=0.032) and hemoglobin (p=0.019). Conclusion: There is a significant relationship between the number of leukocytes and hemoglobin with the incidence of febrile seizures in children.

Hubungan Kejadian Skor Apgar Kurang dari 7 dengan Faktor Risiko Ibu dan Persalinan di RSUD Abdul Wahab Sjahranie Samarinda Tahun 2018-2019: Relationship between Incidence of Apgar Score Less than 7 with Risk Factors for Mother and Childbirth at Abdul Wahab Sjahranie Hospital, Samarinda in 2018-2019 Caecilia Anggi Raharjo; Novia Fransiska Ngo; Annisa Muhyi
Jurnal Sains dan Kesehatan Vol. 3 No. 2 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Asfiksia neonatorum adalah suatu kondisi dimana terdapat gangguan pertukaran gas karbondioksida dan oksigen yang menyebabkan terjadinya hipoksemia dan hiperkarbia pada janin yang berujung pada asidosis yang biasanya dapat dilihat dari skor apgar yang rendah. Asfiksia neonatorum menempati posisi kedua tertinggi penyebab kematian neonatus dengan angka 4 juta kematian setiap tahunnya. Penelitian ini bertujuan untuk mengetahui hubungan antara kejadian skor apgar kurang dari 7 dengan faktor risiko ibu yang terdiri dari usia ibu, paritas, anemia pada saat hamil, dan faktor risiko persalinan yang terdiri dari partus lama. Desain penelitian yang digunakan adalah kasus kontrol dengan sampel penelitian masing-masing sebanyak 46 untuk kelompok kasus dan kontrol. Analisis dilakukan dengan uji chi-square. Hasil penelitian menunjukan bahwa terdapat hubungan antara kejadian skor apgar kurang dari 7 dengan partus lama, serta tidak terdapat hubungan antara kejadian skor apgar kurang dari 7 dengan Usia Ibu, paritas dan Anemia.

Hubungan Status Gizi, Umur, Jenis Kelamin dengan Derajat Infeksi Dengue pada Anak di RSUD Abdul Wahab Sjahranie Samarinda: Relationship between Nutritional Status, Age, Gender and Degree of Dengue Infection in Children at Abdul Wahab Sjahranie Hospital Samarinda Putri Lintang Kharisma; Annisa Muhyi; Eva Rachmi
Jurnal Sains dan Kesehatan Vol. 3 No. 3 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Dengue virus infection can manifest from mild to severe, which are undifferentiated fever, dengue hemorrhagic fever (DD), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS), respectively. Mild and severe dengue infection is difficult to distinguish early in the course of the disease, and the clinical course is also difficult to "predict". Therefore, indicators were needed to predict the degree of dengue virus infection, thus appropriate treatment can be given. The study was aimed to determine the association of nutritional status, age, and sex with the degree of dengue infection in children. This study was an analytic observational study with a cross-sectional design. The samples were pediatric patients (0-18 years), who have been diagnosed with dengue virus infection and were hospitalized at the Abdul Wahab Sjahranie Hospital Samarinda in 2019. Purposive sampling technique was used to appointed 88 patients. The data obtained from the medical records. The bivariate association was statistically analyzed with chi-square test. The result showed a significant association between sex (p = 0.041) with the degree of dengue infection in children. Meanwhile nutritional status (p = 0.127) and age (p = 0.077) had no significant association with the degree of dengue infection in children. In conclusion, sex might serve as a predictor of the degree of dengue infection in children, in which male is more susceptible to worse manifestations.

Hubungan Usia, Kadar Hemoglobin Pretransfusi dan Lama Sakit terhadap Kualitas Hidup Anak Talasemia di Samarinda : Relationship of Age, Pretransfusion Hemoglobin Levels and Length of Sickness on Quality of Life in Children with Thalassemia in Samarinda Hurria Maulana Ali; Annisa Muhyi; Yudanti Riastiti
Jurnal Sains dan Kesehatan Vol. 3 No. 4 (2021): Jurnal Sains dan Kesehatan
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

The Relation between Age, Pre-transfusion Hemoglobin Level and Duration of Sickness on Quality of Life in Children with Thalassemia in Samarinda. Thalassemia is a genetic disease caused bya disturbance in the process of forming the hemoglobin chain of red blood cells that decreased the production or formation of hemoglobin. Children with Thalassemia will have transfusions for their whole life to maintain blood hemoglobin levels. The older age of the child will also increase the frequent of blood transfusions to support the child’s growth. Long and continuous transfusions also inadequate treatment will cause complications that affect the quality of life for people with Thalassemia. This study aims to analyze the relation between age, pre-transfusion hemoglobin level and duration of sickness on quality of life in children with Thalassemia in Samarinda. This research was an analytic observational study with a cross sectional design. The subjects were 32 children, aged 2-18 years, with major Thalassemia who werethe members of POPTI Samarinda. The data collected by medical records and the result from patient’s interview using PedsQl 4.0. Statistical analysis use Pearson Test. The resultshows there isno relation between age and quality of life in children with Thalassemia (p = 0.136), there is relation between pre-transfusion hemoglobin level with the quality of life in children with Thalassemia (p = 0.040) and there is relation between duration of sickness and quality of life in children with Thalassemia (p = 0.036). Based on the results of this study, it can be concluded that age has no relation to quality of life in children with Thalassemia. Pre-transfusion hemoglobin level and duration of sickness have relation to quality of life in children with Thalassemia. Keywords: Thalassemia, quality of life, age, pre-transfusion hemoglobin level, duration of sickness.

Sphingomonas paucimobilis an unusual cause of subdural empyema in pediatric: a case report Annisa Muhyi; Amalia Aswin
Pediatric Sciences Journal Vol. 2 No. 1 (2021): (Available online 1 June 2021)
Publisher : Medical Faculty of Brawijaya University, Indonesia

Introduction: Acute bacterial meningitis continues to be a neurological emergency with high mortality and morbidity Case: We report the case of a pediatric patient with subdural empyema due to Sphingomonas paucimobilis. A 2-month-old infant developed fever, generalized seizures, and worsening general status. He had a cough for two weeks, and a chest X-ray showed pneumonia. Laboratory tests reveal marked leukocytosis, a white blood cell count of 28.500/mL, and an elevated platelet level of 654.000 mg/dL. A computerized brain tomography revealed an empyema subdural. A cerebrospinal fluid analysis showed unclear fluid, revealed cell count 3560 cells, 90% mononuclear and 10% polymorphonuclear, red blood cell count of 0/mm3, protein of 370 mg/dL, and glucose of 35 mg/dL. His cerebrospinal fluid culture showed Sphingomonas paucimobilis sensitive to cephalosporin, levofloxacin, meropenem, imipenem, gentamycin, tobramycin and amikacin. He was treated empirically with meropenem. The patient had a rapid recovery from the seventh day of treatment and was discharged on hospital day 14. Conclusion: We highly recommend raising awareness about subdural empyema as a complication for acute bacterial meningitis caused by S. paucimobilis in community-acquired infection.

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