Irma Dewi Ratnawati
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Journal : Medali Jurnal : Media Dental Intelektual

ANTIBACTERIAL EFFECTS OF BLACK QUICK (Nigella sativa L.) OIL EMULGEL AGAINST Streptococcus mutans (IN VITRO) Irma Dewi Ratnawati; Linda Septiana; Alrevo Panji Auradewa
Jurnal Medali Vol 4: Special Issue 1. Desember 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.4.3.113-122

Abstract

Background: Secondary infection of traumatic ulcer can be caused by Streptococcus mutans. Black seed oil emulgel (Nigella sativa L.) has a saponin that has antibacterial effect on Streptococcus mutans growth. The purpose of this research for know the antibacterial effect of black seed oil emulgel (Nigella sativa L.) on Streptococcus mutans growth in vitro.Method: Experimental laboratory in vitro was held using post-test only control group design. There are four groups: negative control group and black seed oil emulgel in 5%, 7%, and 10%. Disk diffusion method was used in this research. Data analyzed by Anova test.Result: The result indicates some significant effect of black seed oil emulgel on Streptococcus mutans growth from Anova test 0,000(<0,05).Conclusion: It can be concluded that there is antibacterial effect on black seed oil emulgel to Streptococcus mutans growth.
EFFECTIVENESS OF BELUNTAS EXTRACT GEL (Pluchea indica) ON THE GROWTH OF Porphyromonas gingivalis Irma Dewi Ratnawati; Lulu Sa’adah; Budi Suhartono
Jurnal Medali Vol 5, No 2 (2023): Media Dental Intelektual September 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.5.2.125-131

Abstract

Background: Periodontal disease is common in Indonesia, especially periodontitis, with a prevalence of 74.1%. One of the main etiologies of periodontitis is Porphyromonas gingivalis which colonizes dental plaque in the stages of secondary colonization and maturation. Pluchea indica leaves contain active substances with antibacterial properties, including flavonoids, tannins, alkaloids, saponin, and atsiri oil which can be used as additional pharmacotherapeutic therapy in the treatment of periodontitis. The gel preparation has good dispersion, practical, easy to apply. Aim the study to specify the effectiveness of Pluchea indica extract gel 40%, 60% and 80% against the growth of Porphyromonas gingivalis. Method: This research employed an in vitro experimental post-test control design. Thirty samples were split into five groups: the 40%, 60%, and 80% concentrations of the Pluchea indica leaves gel, positive control using metronidazole gel, and negative control. Samples underwent 48 hours of incubation. After being administered a Pluchea indica leaves gel, the diffusion method is used to determine the sensitivity of the test bacteria to antibacterial. Result: The diameter of the inhibition zone formed by Pluchea indica extract gel group with a concentration of around 80% was in the category very strong. Based on the results of the Tukey post-hoc test p