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All Journal Jurnal Biologi Tropis
Fitriannisa Faradina Zubaidi
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Journal : Jurnal Biologi Tropis

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Analysis of Malondialdehyde (MDA) Levels Based on Body Mass Index, Waist Circumstances, and Body Fat Percentage in Students of Medicine Program Faculty of Medicine Mataram University Ida Ayu Eka Widiastuti; Fitriannisa Faradina Zubaidi; Basuki Rahmat; Gede Wira Buanayuda
Jurnal Biologi Tropis Vol. 22 No. 4 (2022): October - December
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v22i4.4513

Abstract

Obesity can cause chronic oxidative stress. Oxidative stress occurs when the formation of free radicals is greatly increased or the protective antioxidant mechanisms are disrupted. Previous studies have concluded that there is a relationship between oxidative stress and excess body weight and obesity. One of the products of oxidative stress is malondialdehyde (MDA). This study aims to determine the correlation between malondialdehyde (MDA) levels and body mass index (BMI), waist circumference (LP), and body fat percentage. The subjects were 55 students of the Medical Education Study Program, Faculty of Medicine, University of Mataram, class of 2021. The BMI variable was calculated by dividing body weight (kg) by the square of height (m), waist circumference was measured using a tape measure (cm), and body fat percentage measured by body composition monitor (%). Serum MDA levels were measured using the ELISA method. Data were analyzed statistically with the Spearman correlation test. The results showed that the average MDA level in subjects with overweight and obesity was higher than normal, however there was no significant correlation between body mass index, waist circumference, and body fat percentage with MDA levels, with each significance value :p=0.230; p=0.276; and p=0.666. Body mass index, waist circumference, and body fat percentage cannot be ruled out as risk factors for oxidative stress.
The Difference in Malondialdehyde (MDA) Levels among Normoweight, Overweight, and Obesity in Student of Medicine Program Faculty of Medicine, Mataram University Ni Putu Visty Widhiani; Ida Ayu Eka Widiastuti; Fitriannisa Faradina Zubaidi
Jurnal Biologi Tropis Vol. 23 No. 3 (2023): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i3.5429

Abstract

Obesity has emerged as a global issue, including in Indonesia. Previous research has shown that obesity causes oxidative stress, which contributes to degenerative diseases such as type II diabetes mellitus, premature aging, cardiovascular disease, tumors and cancer. Malondialdehyde (MDA) is one of the biomarkers used to assess oxidative stress. The aim of this study was to determine differences in MDA levels in medical students at the University of Mataram based on weight criteria: normal, overweight, and obese. The study included 41 students from the 2021 class of the Medical Education program at the University of Mataram who were divided into two groups based on their body mass index (BMI). BMI was determined by isolating body weight (kg) by the square of level (m2), and serum MDA levels were resolved utilizing the ELISA technique. The information were investigated utilizing the Mann-Whitney relative test. The results showed that the MDA level in group 2 (obese and overweight) was 1715.27 ng/ml, higher than group 1 (normoweight) with levels of 902.67 ng/ml. However, this difference was not statistically significant, because the p-value was 0.093 (p > 0.05).
Co-Authors Basuki Rahmat Gede Wira Buanayuda Ida Ayu Eka Widiastuti Ni Putu Visty Widhiani