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Journal : Prominentia Medical Journal

NEUROKARDIOLOGI: INTERAKSI JANTUNG DAN OTAK Sidhi Laksono
Bahasa Indonesia Vol 3 No 2 (2022): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v3i2.3240

Abstract

The heart-and-brain axis is an important connection and is known as neurocardiology. This science combines the specialization of cardiology and neurology in dealing with cases of nervous and cardiovascular systems. Any dysfunction in one of the components will interfere with that of the other component. Abnormalities of the nervous system can result in different changes in the cardiovascular function and structure, ranging from temporary changes in the ECG to myocardial injury, cardiomyopathy, and even cardiac death. This article reviews the anatomy and physiology of the central nervous system (CNS) and autonomic nervous system (ANS) in relation to the control of cardiovascular function in physiological and pathological states. In conclusion, the interaction between the heart and the brain affects one another, therefore, any abnormalities in the brain may cause abnormalities in the heart. It is hoped that knowledge of the heart and brain axis can provide an overview of knowledge about heart abnormalities caused by neurological disorders.
GAGAL JANTUNG DENGAN FRAKSI EJEKSI SEDIKIT MENURUN: SUATU TINJAUAN PUSTAKA Sidhi Laksono
Bahasa Indonesia Vol 4 No 1 (2023): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v4i1.3517

Abstract

The European Heart Association (ESC) 2021 heart failure guidelines introduce a third ejection fraction (EF) category for heart failure with an EF of 40-49%, referred as heart failure with mildly reduced EF (HFmrEF). This category has not been explored much in comparison to heart failure with reduced EF (HFrEF; defined as EF < 40%) and heart failure with normal EF (HF preserved EF, HFpEF; defined as EF 50%). The prevalence of HFmrEF in the population of patients with HF was 10-25%. HFmrEF may be underdiagnosed, given the error and variability in EF measurements and the presence of milder symptoms in these patients compared to patients with HFrEF. The precise recognition and phenotyping of HFmrEF is important as it may support treatment recommendations based on available data. One study showed that survival rate in patients with HFmrEF or HFrEF is lower compared to patient with HFpEF. The characteristics of HFmrEF are more similar to HFrEF. Further studies are needed to fill the information gap in the case of HFmrEF.