Atan Baas Sinuhaji, Atan Baas
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Hepatitis Akibat Penyakit Sistemik Daulay, Dedy Gumilang; Supriatmo, Supriatmo; Sinuhaji, Atan Baas
Sari Pediatri Vol 8, No 4 (2007)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp8.4.2007.294-8

Abstract

Hati merupakan organ parenkim terbesar yang sering terlibat akibat penyakit sistemik.Pada beberapa penyakit sistemik, hati dapat lebih bertahan dibanding organ tubuhlainnya. Dalam mengevaluasi pasien dengan disfungsi dan penyakit sistemik, klinisiharus dapat membedakan apakah gangguan hati yang terjadi akibat penyakit sistemik,akibat obat yang digunakan dalam terapi penyakit sistemik tersebut ataupun bersamaandengan penyakit hati primer
Effect of vitamin A on severity of acute diarrhea in children Marpaung, Marlisye; Supriatmo, Supriatmo; Sinuhaji, Atan Baas
Paediatrica Indonesiana Vol 53 No 3 (2013): May 2013
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.171 KB) | DOI: 10.14238/pi53.3.2013.125-31

Abstract

Background Vitamin A deficiency may increase the risk or bea cause of diarrhea. Many studies have been conducted on theefficacy of vitamin A in the management of acute diarrhea, butthe outcomes remain inconclusive.Objective To determine the effectiveness of vitamin A in reducingthe severity of acute diarrhea in children.Methods We performed a single􀁈blind􀁈randomized controlledtrial in the Secanggang District, Langkat Regency, North ofSumatera, from August 2009 to January 2010 in children aged6 months to 5 years, who had diarrheas. Subjects were dividedinto two groups. Group 1 received a single dose of vitamin A(100,000 IU for subjects aged 6 to 11 month old or with bodyweights :s 10 kg, or 200,000 IU for subjects aged 2: 12 month oldor with body weights> 10 kg). Group 2 received a single doseof placebo. The establishment of severity was based on changesin diarrheal frequency, stool consistency, volume and durationof diarrhea after treatment. We performed independent T􀁈testand Chi square tests for statistical analyses. The study was anintention􀁈to􀁈treat analysis.Results We enrolled 120 children who were randomized intotwo groups of 60 subjects each. Group 1, received vitamin Aand group 2 received a placebo. The results showed significantdifferences between the two groups in stool volume starting onthe first day (95%CI 192.30 to 3237.51; P􀁉O.OOI), as well asdiarrheal frequency (P=O.OOl) and stool consistency (P=O.OOl)on the second day observation and duration of diarrhea followingtreatment (95%CI - 40.60 to - 25.79; P􀁉O.OOI;).Conclusions Vitamin A supplementation is effective in reducingthe severity of acute diarrhea in children under five years of age.[Paediatr lndones. 2013;53:125-31.]
Obesity and functional constipation in children Yuwanita, Natasha; Sinuhaji, Atan Baas; Sembiring, Tiangsa; Supriatmo, Supriatmo; Yudiyanto, Ade Rachmat
Paediatrica Indonesiana Vol 58 No 1 (2018): January 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.628 KB) | DOI: 10.14238/pi58.1.2018.1-4

Abstract

Background Functional constipation is a common pediatric problem in both developed and developing countries.  In the past two decades, the prevalence of obesity has increased worldwide. Obesity itself leads to many health problems, including functional constipation. Studies correlating obesity to functional constipation have thus far mostly originated from developed countries.Objective To assess for a possible correlation between obesity and functional constipation in children in a developing country.Methods This cross-sectional study was conducted in Al-Mukhlisin Islamic Boarding School, Batu Bara District, North Sumatera Province, Indonesia, between July and August 2015. The subjects were 150 students aged 12 to 17 years. Questionnaires were used to determine functional constipation and filled by direct interview. Obesity was determined by body mass index. Data were analyzed using Chi-square test.Results Of 150 children, 49 had functional constipation; and 18 of the 49 were obese. The mean age of children with constipation was 14.7 (SD 1.07) years (95%CI 14.1 to 14.7) and their mean body weight was 53.8 (SD 15.10) kg (95%CI 49.4 to 58.1). The prevalence for functional constipation in obese children was  58% There was a statistically significant correlation between obesity and functional constipation (prevalence ratio=4; 95%CI 1.72 to 8.94; P=0.001), indicating that obese children had 4 times higher risk of having functional constipation.Conclusion There is a significant correlation between obesity and functional constipation in children.
Efficacy of fructooligosaccharide versus placebo for treatment of acute diarrhea in children: A double-blind randomized clinical trial Suryanty, Reni; Supriatmo, Supriatmo; Hasibuan, Berlian; Sinuhaji, Atan Baas
Paediatrica Indonesiana Vol 45 No 2 (2005): March 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.2.2005.65-8

Abstract

Objective To compare the efficacy of fructooligosaccharide (FOS)versus placebo in pediatric patients with acute diarrhea with re-gard to duration and frequency of diarrhea and the volume andconsistency of the stools.Methods This double-blind randomized clinical trial was carriedout from July to November 2003 in the pediatric intensive careunit, outpatient clinic, and pediatric ward of Adam Malik Hospitaland Pirngadi Hospital, Medan. Subjects were children and infantsaged 4 to 24 months suffering from acute diarrhea without dehy-dration or with mild to moderate dehydration whose parents gaveconsent. Children included in this trial received tablets of either600 mg FOS or 761 mg fructulin as placebo. Patients with mild tomoderate dehydration were initially rehydrated according to theWHO protocol. Afterwards, 10 tablets of FOS or placebo were givento each subject to be taken twice daily. In subjects without dehy-dration, the tablets were given by their parents. Daily follow-upwas performed, in which body weight, temperature, duration andfrequency of diarrhea, and the volume and consistency of stoolswere recorded. For outpatients, home visits were made.Results Out of 142 children who met inclusion criteria, 135 com-pleted the study. These consisted of 68 children in the FOS groupand 67 in the placebo group. Subjects were mostly <12 months ofage (57.0%), male (57.8%), and moderately malnourished (34.1%).There was no statistically significant difference between both groupsin the duration and frequency of diarrhea and the volume and con-sistency of stools (P>0.05).Conclusion There is no effect of the administration of FOS assupplemental therapy on the duration and frequency of diarrheaand on the volume and consistency of stools in children with acutediarrhea
Comparison of zinc-probiotic combination therapy to zinc therapy alone in reducing the severity of acute diarrhea Hatta, Muhammad; Supriatmo, Supriatmo; Ali, Muhammad; Sinuhaji, Atan Baas; Hasibuan, Berlian; Nasution, Fera Luna
Paediatrica Indonesiana Vol 51 No 1 (2011): January 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.1.2011.1-6

Abstract

Background Although the incidence of diarrhea in Indonesia has declined in the last five years, the mortality rate in children under five years old is still high. Therefore, appropriate and comprehensive management of diarrhea is essential. There have been many studies on the role of zinc therapy and probiotic therapy in reducing the severity of acute diarrhea, but not many studies have compared the use of a combination of the two therapies tozinc therapy alone.Objective To compare the efficacy of zinc-probiotic combination therapy to zinc alone in reducing the severity of acute diarrhea.Methods We conducted a randomized, open-label, controlled trial from July 2009 to January 2010 in Adam Malik Hospital and Pirngadi Hospital, Medan. Children aged between 1 month and 5 years who met the criteria were divided into two groups. Group I received zinc sulphate (aged <6 months: 10 mg/day; aged 2:6 months: 20 mg/day) combined with heat-killed Lactobacillus acidophilus (3x101O CFU/day) for 10 days. Group II received only zinc sulphate at the same dosage as group I. Measurement of disease severity was based on the frequency of diarrhea (times/day) and the duration of diarrhea (hours) after initial drug consumption.Results Eighty subjects were enrolled, randomised, and divided equally into two groups. 40 children received zinc-probiotic in combination (group I) and the remainder (group II) received zinc alone. We observed significant differences in frequency of diarrhea (2.1 vs 3.1 times/day, P=0.001, 95%CI -1.62 to -0.49), and duration of diarrhea (52.1 vs. 72.6 hours, P=0.00l, 95%CI -30.91 to -10.18) in the two groups.Conclusion Combination of zinc-probiotic therapy was more effective in reducing the severity of acute diarrhea than zinc therapy alone in children under five years of age.
Steatocrit Value in New-Born Babies Usman, Johnwan; Abdullah, Irfan; Muhazar, Muhazar; Sinuhaji, Atan Baas; Sutanto, A. H.
Paediatrica Indonesiana Vol 35 No 7-8 (1995): July - August 1995
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi35.7-8.1995.190-3

Abstract

A prospective study on steatocrit value in full-term or preterm newborn babies of~ 2 days of age in Dr. Pimgadi Hospital, Medan is reported. This study was conducted from December 7, 1992, to February 7, 1993; there were 72 newborn babies (37 males and 35 females). The body weight was> 2500 gin 60 babies and s. 2500 gin 12 babies. The median steatocrit value in babies with body weight of> 2500 g was 9%, and it was 32% in babies less than 2500 g of body weight. The proportion of babies with > 25% steatocrit value was larger in babies less than 2500 g than that in 2500 g by the diet patterns of breast milk, breast milk and milk formula, milk formula. The proportion of babies with < 25% steatocrit value was higher in babies with body weight of< 2500 g than that in babies > 2500 g for those who had either breast milk, breast milk and milk formula or milk formula. There was significant difference (p<0,05) in the steatocrit levels between babies with the body weight of > 2500 g and those who had body weight of ≤ 2500 g.
Lansoprazole for recurrent abdominal pain in adolescents Surya, Ade Saifan; Nafianti, Selvi; Deliana, Melda; Supriatmo, Supriatmo; Sinuhaji, Atan Baas
Paediatrica Indonesiana Vol 51 No 4 (2011): July 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.4.2011.234-40

Abstract

Background Recurrent abdominal pain is common among adolescents. School absenteeism and lower quality of life are associated with severity of symptoms. Lansoprazole has been used to treat recurrent abdominal pain.Objective To investigate the effectiveness of lansoprazole as a treatment for recurrent abdominal pain in adolescents.Methods We conducted a randomized, double-blind, controlled trial from August 2009 to October 2009. Adolescents suffering recurrent abdominal pain were eligible for the study. Simple randomization was done to divide subjects into two groups. Groups received 30 mg of lansoprazole or placebo, once a day for 14 days. Before treatment, we performed laboratory and physical examinations. Pain frequency was measured in number of abdominal pain episodes per month. Duration was measured in minutes and pain intensity was measured by a pain rating scale. Drug efficacy was measured before, during and after intervention. Data was analyzed using Mann-Whitney U-test and t-test.Results One hundred sixteen recurrent abdominal pain patients were randomized into two groups of 58 patients. There were no statistically significant differences in pain frequency before and after treatment for either the lansoprazole group or the placebo group (P=0.083, 95%CI, -0.033 to 0.021 and P=0.096, 95%CI -0.376 to 0.031, respectively). In addition, there were no significant differences in frequency, duration, and degree of abdominal pain at baseline and after 1, 2 and 3 months of treatment between the two groups.Conclusion Lansoprazole was not more effective than the placebo for treatment of recurrent abdominal pain among adolescents.
Manfaat pemberian gabungan selenium dan probiotik pada pengobatan konstipasi fungsional pada anak Lestari, Wahyu Ningsih; Sinuhaji, Atan Baas; dr, Supriatmo
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 45, No 2 (2012): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Constipation is a common health problem in children and can cause serious problems. The prevalence of constipation in childrenvaries from 0.7% to 29.6% and most of constipation in children (> 90%) is functional in the absence of organic abnormalities.Probiotics are living microorganisms when administered in sufficient quantities will benefit the host. Probiotic bacteria in thegut can increase intestinal motility, improve stool consistency and increase the frequency of defecation so effective in thetreatment of constipation. Selenium is an essential micronutrient required by the majority of the body's organ systems to functionproperly. Oxidative stress thought to be involved as one of the factors causing constipation. Selenium as an antioxidant cantreat functional constipation in children, because the main function of selenium is a cofactor of glutathione peroxidase, whichprotects membranes from oxidative damage.Keywords : functional constipation; selenium; probiotic
Peranan amitriptilin pada pengobatan dispepsia fungsional Mustawa, Indra; dr, Supriatmo; Sinuhaji, Atan Baas
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 45, No 3 (2012): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Functional dyspepsia is common in adolescents. School absenteeism and poor quality of life are associated with the severity of the symptoms. Pathophysiology of functional dyspepsia is very heterogeneous. Currently there is no satisfactory therapy in the treatment of functional dyspepsia. Biopsychosocial factor is one of the contributing factor causing the symptoms of functional dyspepsia. One of the alternative therapy is Tricyclic antidepressant (TCA) such as amitriptyline. Amitriptyline is theoretically advantageous because their overall effect on the brain-gut axis, both at the center and in the intestine.Keywords: amitriptyline; functional dyspepsia; adolescent
Hubungan kejadian gejala refluks gastroesofageal dengan konstipasi fungsional pada anak Loka, Herlina; Sinuhaji, Atan Baas; dr, Supriatmo; Yudiyanto, Ade Rachmat
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 3 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Constipation and gastroesophageal reflux are commonly found in the childhood. Delayed colonic transit time in children with functional constipation made the children experience gastroesophageal reflux symptoms such as regurgitation, vomiting, acid regurgitation, pyrosis, hiccup, belching, difficulty in swallowing and chronic cough.Keywords: gastroesophageal reflux; constipation; regurgitation; children