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All Journal Journal of General-Procedural Dermatology & Venereology Indonesia
Roesyanto-Mahadi, Irma Damayanti
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Medicine & Pharmacology

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Journal : Journal of General-Procedural Dermatology

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Allergic contact dermatitis due to nickel in household detergent Putri, Dewi Utami; Roesyanto-Mahadi, Irma Damayanti
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 2
Publisher : UI Scholars Hub

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Abstract

Allergic contact dermatitis (ACD) is a cutaneous inflammatory reaction caused by contact with specific exogenous allergen to which a person has developed allergic sensitization. Nickel was reported as one of the most common causes of ACD worldwide, particularly affecting females. It is associated with a variety of nickel-containing products, from jewelry to detergent. A 32-year-old female was presented with pruritic eruption consist of erythematous papules and vesicles on both hands and extensor forearms since 2 weeks before admission. The patient is a housewife who did handwashing clothes and kitchenware with detergent and soap every day. At first, there were erythematous papules on the right extensor forearm, then the patient wore rubber gloves to protect hands when washing. However, the lesions spread to the left extensor forearm and there were also vesicles on both hands. There was history of localized reactions to metal items, the latter one was 3 weeks ago after wearing a metal necklace. The clinical presentation were multiple erythematous papules and vesicles, erythematous and hyperpigmented macules. The patch test using Chemotechnique Diagnostics AB and square chamber showed a 2+ reaction to nickel sulphate. The patient was educated to avoid the causative allergen and treated with oral antihistamine and topical corticosteroid. The patient showed significant clinical improvement after 2 weeks. Nickel as metal catalyst used in detergents is found in small concentration, but can lead to ACD in an already sensitized individual. The lesions persist despite the use of gloves because nickel is absorbed through rubber material.
Dermoscopic and histopathologic findings in diagnosing postpartum pemphigoid gestationis Chandra, Rudi; Roesyanto-Mahadi, Irma Damayanti
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 1
Publisher : UI Scholars Hub

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Background: Pemphigoid gestationis (PG) is an uncommon autoimmune vesiculobullous skin disorder associated with pregnancy, that occurs during mid-to-late pregnancy and immediate postpartum period. The diagnosis of PG is based on histopathology and direct immunofluorescence. Dermoscopy is a non-invasive diagnostic tool that provides a connection between macroscopic clinical dermatology and microscopic dermatopathology. Case Illustration: We reported a case of a 22-year-old primigravida woman with postpartum PG. This PG case was diagnosed clinically, dermoscopically, and histopathologically. Discussion: Since PG is thought to be a variation of the bullous pemphigoid (BP), the two resemble each other clinically and immunologically. The well-defined structures with brown-black dots in the central, yellowish translucent areas, follicular openings, peri-eccrine and perifollicular pigmentations, and a distorted pigment network were the dermoscopic findings of PG. To date, there is no literature about the dermoscopic features of PG. Conclusion: Dermoscopy is a simple non-invasive tool that can assist in making a rapid diagnosis, as well as in evaluating the prognosis, observing the response to treatment, and helping to determine the appropriate lesion and location for histopathological examination. We recommend that the dermoscopic features of PG in our case as a dermoscopic picture of PG.
Co-Authors Putri, Dewi Utami Rudi Chandra