This study aims to find out how to optimize the application of game-based learning models in 21st century learning in elementary schools. The research method used in this research is library research with qualitative research. Implementation of game-based learning in the learning process used by students can be an innovative solution to solve various learning problems. Innovative learning in the 21st century has characteristics that lead to learning that is interactive, holistic, integrative, scientific, contextual, thematic, effective, collaborative, and socialization to students, and the implementation of learning is directed using learning models/methods related to these characteristics. It can be concluded that Game-Based Learning is suitable as an innovation in learning. because the results of the preliminary study show that Game-Based Learning is effective and efficient and based on literature studies Game-Based Learning has many benefits and advantages which are its advantages