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Septiani Mimin
Department of Chemical Engineering, Ujung Pandang State Polytechnic, Makassar 90254, South Sulawesi,Indonesia
Chemical Engineering, Chemistry & Bioengineering

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Journal : Indonesia Chimica Acta

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The Synthesis, Characterization Gd(Iii) Complex with Heptilmethyl- Ditiocarbamate and 2,9-Dimethyl Phenanthroline as Anti-Tuberculosis Muhammad Arham Yunus; Raya Indah; Nurfiansyah Nurfiansyah; Septiani Mimin
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 16, No 1: June 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v16i1.26900

Abstract

Mycobacterium tuberculosis is a bacterium that causes tuberculosis infection disease. The aim of this study was to produce complex compounds that have the ability to damage the cell wall of Mycobacterium tuberculosis. Gd(III)Heptylmethyldithiocarbamate 2,9-dimethyl phenanthroline complex was synthesised and characterised by reacting N-heptylmethylamine, carbondisulphide, 2,9-dimethyl phenanthroline and lanthanide group metal ion (Gadolinium) using in situ method. Characterisation was carried out using electrothermal melting point, conductometer, UV-Vis spectrophotometer, and FT-IR spectrophotometer. The resulting Gd(III)Heptylmethyldithiocarbamate 2,9-dimethyl phenanthroline complex was white in colour as much as 7.01%, conductivity 20 Ω-1 and melting point 208-210o C. Testing of complex compounds gave effective results as antibacterial Mycobacterium tuberculosis.
Co-Authors Muhammad Arham Yunus Nurfiansyah Nurfiansyah Raya Indah