MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan
Vol 2, No 4 (2018): August

Mekanisme Regenerasi Hati secara Endogen pada Fibrosis Hati

Fathiyah Safithri (FK UMMalang, Malang)



Article Info

Publish Date
22 Mar 2018

Abstract

Mechanism of Endogenous Liver Regeneration in Liver Fibrosis Hati merupakan organ unik yang mempunyai kemampuan regenerasi yang luar biasa. Kemampuan regenerasi ini terjadi sepanjang usia manusia. Terapi fibrosis hati  yang berkembang saat ini lebih banyak terfokus pada bagaimana mengobati sel/ jaringan yang sakit berdasarkan patogenesis dan melupakan potensi sel-sel sehat. Sel sehat ini masih mempunyai potensi untuk regenerasi dan memperbaiki daerah yang sakit. Bila kedua hal ini dapat dilakukan bersama-sama maka akan mempercepat proses regenerasi hati. Artikel ini akan mengeksplorasi kontribusi hepatosit, sel stelata, sel punca endogen, sel Kupfer, dan enzim proteolitik pada proses homeostasis dan perbaikan hati khususnya pada kondisi fibrosis. The liver is a unique organ that has remarkable capacity for regeneration. This regenerative potential occurs throughout human life. Currenly treatment of liver fibrosis focuses more on how to treat diseased cells / tissues based on pathogenesis and forget the potential of healthy cell. These healthy cell still havecapability to regenerate and repair the affected areas. If both things are done done together it will accelerate the process of liver regeneration. This article will explore the contributions of hepatocytes, stellate cells, endogenous stem cells, Kupfer cells, and proteolytic enzymes in homeostasis and liver repair processes, especially in conditions of fibrosis

Copyrights © 2018






Journal Info

Abbrev

APKKM

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Magna Medica is a medical journal of APKKM contains papers and scientific articles created as a form of realization Tridharma college. The journal is published every six months, April and October of three articles in the form of: - Research article - Case report - Literature review The scope of this ...