Journal of Dentomaxillofacial Science
Vol. 4 No. 3 (2019): (Available online: 1 December 2019)

The effectiveness methanol extract clausena excavate on number of fibroblast and density of collagen fibers after tooth extraction

Efa Ismardianita (Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Baiturrahmah, Padang, Indonesia)
Widyawati Widyawati (Department of Conservative, Faculty of Dentistry, University of Baiturrahmah, Padang, Indonesia)
Dewi Elianora (Department of Pediatric Dentistry, Faculty of Dentistry, University of Baiturrahmah, Padang, Indonesia)
Wenny Rosalina (Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Baiturrahmah, Padang, Indonesia)
Lusi Nofrike (Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Baiturrahmah, Padang, Indonesia)
Vivi Y. Khairani (Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Baiturrahmah, Padang, Indonesia)



Article Info

Publish Date
01 Dec 2019

Abstract

Objective: This study is made to identify the effect of extracts in Clausena excavata 50% on the number of fibroblasts and the density of collagen fiber in recovery after tooth extraction. Material and Methods: This is a true experimental designed with post-test only control group design, using 24 rats were divided into two groups, each group of three rats. Lower incisor tooth extraction performed lower left, into the tooth socket CMC applied to the control group and 0.5% extract treatment group Clausena excavata 50%. The number density of fibroblasts and collagen fibers were observed on days 3, 7, 14 and 21 with Haematoxylin Eosin staining and Mallory. The differences in density of collagen fibers observation group with Kruskal-Wallis test.Results: There are significant differences in a number of fibroblasts and density of collagen fibers between a control group and socket treatment group (p <0.05).Conclusion: The extract Clausena excavata 50% can fasten the wound recovery by increasing the number of fibroblasts and collagen fibers.

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Journal Info

Abbrev

jdmfs

Publisher

Subject

Dentistry

Description

Journal of Dentomaxillofacial Science (J Dentomaxillofac Sci) is an international, peer-reviewed, and open access journal published in English language. Our journal aims to keep dentists informed of developments and advances in general dentistry and its different specialties in an easy-to-read ...