International Journal of Public Health Science (IJPHS)
Vol 2, No 3: September 2013

Immune Status of HIV – Positive Children with Acute Rhinosinusitis

Nuritdin Narzullaev (Bukhara State Medical Institute)
Suleyman Suleymanov (Bukhara State Medical Institute)
Adolat Ismailova (Institute of Immunology of the Uzbekistan Academy of Science)
Rano Sabitova (nstitute of Immunology of the Uzbekistan Academy of Science)



Article Info

Publish Date
01 Sep 2013

Abstract

The immune status of 25 HIV-positive children with Acute Rhinosinusitis (ARS) has been studied in comparison with the control group of 14 practically healthy children of the same age. HIV-infected patients with ARS have shown deep infringements of the immune status, especially of T-cells and its subpopulations, and impairments of the humoral immunity, suppression of anti-inflammatory cytokine IL-10 and increase of pro-inflammatory IFN-γ. After conducted treatment we have not seen any certain changes of the immune status in HIV positive patients, even in the cases with clinical improvement. It is possible to ascertain only positive changes of IL-10 maintenance and parallel decrease of IFN-γ in the dynamics of treatment.DOI: http://dx.doi.org/10.11591/ijphs.v2i3.2904

Copyrights © 2013






Journal Info

Abbrev

IJPHS

Publisher

Subject

Health Professions

Description

International Journal of Public Health Science (IJPHS) is an interdisciplinary journal that publishes material on all aspects of public health science. This IJPHS provides the ideal platform for the discussion of more sophisticated public health research and practice for authors and readers world ...