Communication in Biomathematical Sciences
Vol 3, No 1 (2020)

THE COVID-19 OUTBREAK IN GERMANY – MODELS AND PARAMETER ESTIMATION

Heidrich, Peter (Mathematical Institute, University of Koblenz?Landau, 56070 Koblenz)
Schäfer, Moritz (Mathematical Institute, University of Koblenz?Landau, 56070 Koblenz)
Nikouei, Mostafa (Mathematical Institute, University of Koblenz?Landau, 56070 Koblenz)
Götz, Thomas (Mathematical Institute, University of Koblenz?Landau, 56070 Koblenz)



Article Info

Publish Date
10 Jul 2020

Abstract

Since the end of 2019 an outbreak of a new strain of coronavirus, called SARS?CoV?2, is reported from China and later also from other parts of the world. Since 21 January 2020, World Health Organization (WHO) reports daily data on confirmed cases and deaths from both China and other countries [1]. The Johns Hopkins University [2] collects those data from various sources worldwide on a daily basis. For Germany, the Robert?Koch?Institute (RKI) also issues daily reports on the current number of infections and infection related fatal cases and also provides estimates of several disease-related parameters [3]. In this work we present an extended SEIRD?model to describe these disease dynamics in Germany. The model takes into account the susceptible, exposed, infected, recovered and deceased fractions of the population. Epidemiological parameters like the transmission rate, lethality or the detection rate of infected individuals are estimated by fitting the model output to available data. For the parameter estimation itself we compare two methods: an adjoint based approach and a Monte?Carlo based Metropolis algorithm.

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Journal Info

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Publisher

Subject

Social Sciences

Description

Full research articles in the area of Applications of Mathematics in biological processes and ...