Journal of Dentomaxillofacial Science
Vol. 5 No. 2 (2020): (Available online: 1 August 2020)

Changes in osteoblast and osteoclast cell count after moringa oleifera leaf extract administration during orthodontic tooth movement

Rika D. Syarif (Department of Orthodontic, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia)
Tuti Kusumaningsih (Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia)
Ira Arundina (Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia)



Article Info

Publish Date
01 Aug 2020

Abstract

Objective: The aim of this study was to analyze the effect of moringa leaf extract administration at 5%, 10%, and 20% concentration toward osteoblast and osteoclast cell count in tension area of Cavia cobaya tooth movement. Matrial and Methods: This study was an experimental research with post test only control group design conducted on Cavia Cobaya. The samples were divided into 4 groups, namely control group (given orthodontic forces), P1 group (given orthodontic forces and Moringa oleifera extract at 5% concentration), P2 group (given orthodontic forces and Moringa oleifera extract at 10% concentration) and P3 group (given orthodontic forces and Moringa oleifera extract at 20% concentration). The samples were sacrificed in day 15 and the tissue were collected for histological examination to examine osteoblast and osteoclast cell count.Results: The Anova test showed a significant difference of osteoblast and osteoclast cell count among groups (p<0.05).Conclusion: Moringa leaves extract administration at 20% concentration for 7 days shows higher number of osteoblast and osteoclast compared to control group, 5% and 10% extract group.

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Journal Info

Abbrev

jdmfs

Publisher

Subject

Dentistry

Description

Journal of Dentomaxillofacial Science (J Dentomaxillofac Sci) is an international, peer-reviewed, and open access journal published in English language. Our journal aims to keep dentists informed of developments and advances in general dentistry and its different specialties in an easy-to-read ...