Jurnal Teknologi Reaktor Nuklir Tri Dasa Mega
Vol 23, No 1 (2021): FEBRUARY 2021

DOSE OPTIMIZATION ON LIVER CANCER PROTON THERAPY AND BORON NEUTRON CAPTURE THERAPY USING PARTICLE AND HEAVY IONS TRANSPORT CODE SYSTEM

Hafiz Fahrurrozi (Universitas Gadjah mada)
Andang Widi Harto (Universitas Gadjah Mada)
Isman Mulyadi Triatmoko (National Nuclear Energy Agency)
Gede Sutrisna Wijaya (National Nuclear Energy Agency)
Yohannes Sardjono (National Nuclear Energy Agency)



Article Info

Publish Date
17 Feb 2021

Abstract

Liver cancer was the third leading cause of death from cancer in 2020 with 830,180 deaths worldwide. Radiotherapy is a common treatment method for liver cancer. Technological advances presented proton therapy and boron neutron capture therapy (BNCT) as alternatives with a lower dose on healthy organs. The objective of this research is to get a good dose distribution with higher tumor dose and lower healthy organ dose in proton therapy. A comparison with BNCT is done to get a better understanding of how both methods deliver the dose to treat the cancer while minimizing healthy organ doses. The research simulated proton therapy for cancer liver with Particle and Heavy Ions Transport Code System (PHITS), and a literature review for BNCT. The effectiveness of both methods were compared by tumor dose and liver dose. The optimal tumor dose for proton therapy is 86.01 Gy (W) with 0.67 Gy (W) liver dose. Proton therapy can replace conventional radiotherapy for tumors with complex shapes in dose delivery by utilizing its dose profile, while BNCT can give better tumor control on patients previously treated with conventional radiotherapy.

Copyrights © 2021






Journal Info

Abbrev

tridam

Publisher

Subject

Energy Materials Science & Nanotechnology

Description

Jurnal Teknologi Reaktor Nuklir "TRI DASA MEGA" adalah forum penulisan ilmiah tentang hasil kajian, penelitian dan pengembangan tentang reaktor nuklir pada umumnya, yang meliputi fisika reaktor, termohidrolika reaktor, teknologi reaktor, instrumentasi reaktor, operasi reaktor dan lain-lain yang ...