Jurnal Kedokteran
Vol 9 No 4 (2020): Jurnal Kedokteran volume 9 no 4 2020

PROFIL EFEK SAMPING PENGGUNAAN ANTIRETROVIRAL PADA PENDERITA HIV/AIDS DI POLIKLINIK VCT DI KOTA MATARAM TAHUN 2019

Mitha Yunda Pertiwi (Unknown)
Indah Sapta Wardani (Unknown)
A.A Ayu Niti Wedayani (Unknown)



Article Info

Publish Date
11 Jan 2021

Abstract

Background: In treating HIV infection, Indonesia uses the fast track 90-90-90 approach, which one indicator is giving early ARV treatment to infected patients. First line ARV used in Indonesia today is a fixed-dose combination (FDC) consisting of tenofovir, lamivudine/emtricitabine, and efavirenz. ARV use might cause adverse drug reactions (ADR) with ADR range from mild to severe in HIV patients. This research aims to identify the adverse drug reactions caused by ARV in HIV/AIDS patients in VCT Polyclinic in Mataram City in 2019. Methods: This research is a quantitative descriptive study done in VCT Polyclinic in Mataram city. The subjects are HIV patients in VCT Polyclinic in Mataram city who had met the criteria. This research used secondary data from patients’medical records. Result: Total subjects are 27 patients. ADR occurred in 8 patients (29.6%). These ADR were found in 7 patients using atripla with malaise, dizziness, vomiting, and increased SPOT/SGPT being the most common ADR. One patient using duviral/neviral were found with nausea, vomiting, and itchiness. These ADR came 100% from first degree drug toxicity. Conclusion: The most common ADR were vomiting, malaise, dizziness, and increased SGOT/SGPT. All adverse drug reactions were mild (first degree) therefore therapy was continued and there was no need to consider switching treatment. Keywords: HIV infection, ARV, Atripla, Duviral/Neviral, side effects, first degree

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Journal Info

Abbrev

jk

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

The Unram Medical Journal managed by the Medical Faculty of Mataram University is a scientific journal to publish the results of the latest research in the field of medical and health related. This journal promote medical sciences generated from basic sciences, clinical, and community research to ...