Jurnal Ilmu Bedah Indonesia
Vol. 35 No. 2 (2007): Desember 2007

Experience in the Surgical Management of Two Cases with Acromegaly

Eka J Wahjoepramono (Faculty of Medicine - Pelita Harapan University/ Neurosurgery Departement Siloam Hospital Lippo Karawaci, Banten)

Article Info

Publish Date
02 Aug 2021

Abstract

Acromegaly is a chronic disorder that usually develops over many years due to long term exposure to elevated levels of growth hormone (GH) most typically caused by a somatotrophic cell pituitary adenoma. It has an annual incidence of approximately 3-4 cases / million. A diagnosis of acromegaly is made based on the clinical presentation, biochemical and radiologic finding. The classical feature is the change in appearance and acral enlargement. No single therapy is comprehensively successful in controlling the disease. Surgical, medical and radiation treatments are available for lowering GH and insulin-like growth factor I (IGF-I) hypersecretion, controlling pituitary tumor mass effects, and lowering morbidity.

Copyrights © 2007




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Journal Info
Jurnal Ilmu Bedah Indonesia
Website

Abbrev

Jibi-ikabi

Publisher

Ikatan Ahli Bedah Indonesia

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology

Description

The Indonesian Journal of Surgery (JIBI) is a peer-reviewed and open access journal focuses on publishing journals in the scope of surgery. JIBI accepts any kind of manuscript(s) related to surgery, i.e. original article, meta–analysis, systematic review, comprehensive review, case report, serial ...