Jurnal Sains dan Kesehatan
Vol. 3 No. 3 (2021): Jurnal Sains dan Kesehatan

Invitro: Evaluasi Aktifitas Peluruhan Batu Ginjal Ekstrak Daun Kemangi (Ocimum Basilicum) Menggunakan Spektrofotometer Serapan Atom: Invitro: Evaluation of Anticalculi Activity with Kemangi Leaf Extract (Ocimum Basilicum) Using Atomic Absorption Spectrophotometer

Meliza Harianja (Jurusan Farmasi, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Jambi, Jambi)
Havizur Rahman (Jurusan Farmasi, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Jambi, Jambi)
Sri Wigati (Prodi Kesehatan Hewan, Fakultas Peternakan, Universitas Jambi, Jambi)



Article Info

Publish Date
30 Jun 2021

Abstract

A kidney stone is a disease that is quite often found in the community. Kidney stone disease is characterized by the formation of small stones due to precipitation in the urine. This stone can clog urethra and cause pain. The most common kidney stone content is calcium oxalate. Kemangi (Ocimum basilicum) contains several secondary metabolites such as flavonoids, saponins, phenols, and tannins. The content of secondary metabolites is thought to shed kidney stone. This study aims to reveal other properties of kemangi plant as anticalculi. Method: The stages in this study consisted of making kemangi leaf ethanol extract, extract characterization, phytochemical extract screening, kidney stone calcium making, and kidney stone calcium decay test stage. Testing the effect of the destruction of kidney stone is carried out in vitro by testing the rate of decay of kidney stone calcium components in various concentrations of ethanol extracts of kemangi leaf in physiological NaCl. Kidney stone calcium decay was analyzed by atomic absorption spectrophotometer (ASS). Data were analyzed with one-way ANOVA and continued with the LSD test. Results: ethanol extract of kemangi leaf at a concentration of 600 ? x ?1600 ppm could shed kidney stone calcium significantly greater than negative controls. Conclusion: the kemangi leaf ethanol extract has potential as the destruction of kidney stone.

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Journal Info

Abbrev

jsk

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Jurnal Sains dan Kesehatan (J. Sains. Kes) (e-ISSN 2407-6082, p-ISSN 2303-0267), is a national journal with ISSN and published four times a year in 2015. In 2016 the publishing frequency changed to twice a year. In 2021 the frequency increased to six times a year. Jurnal Sains dan Kesehatan is ...