<![CDATA[Poisson regression analysis is a method used to analyze the relationship between predictor variables and response variables with a Poisson distribution. However, not all data have an orderly pattern, so the Poisson regression is not appropriate to use. To solve this problem, a multivariable Poisson nonparametric regression with a spline truncated estimator was used. In this research, the estimation parameters of multivariable Poisson nonparametric regression was applied to data of infant mortality rates in South Sulawesi in 2017. The infant mortality rate can be measured from the number of infant deaths under one year. The method of selecting the optimal knot point uses the Generalized Cross Validation (GCV) method. The best model is formed on a linear spline model with one knot point. Based on the estimation of the parameters formed, it shows that the variable number of babies with low birth weight (x1) and the number of infants who are exclusively breastfed (x3) significantly affect the number of infant deaths. Keywords: GCV, Multivariable Nonparametric Regression, Poisson, Spline Truncated, Total Infant Mortality.]]>
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