Bioscientia Medicina : Journal of Biomedicine and Translational Research
Vol. 5 No. 12 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research

Coronary Microvascular Dysfunction

Doharjo Manullang (Subspesialized Training, Cardiovascular Division, Department Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Imran Soleh (Cardiovascular Division, Department Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Rukiah Chodilawati (Cardiovascular Division, Department Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Syamsu Indra (Cardiovascular Division, Department Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Ferry Usnizar (Cardiovascular Division, Department Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Erwin Sukandi (Cardiovascular Division, Department Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Taufik Indrajaya (Cardiovascular Division, Department Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Ali Ghanie (Cardiovascular Division, Department Internal Medicine, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)



Article Info

Publish Date
19 Nov 2021

Abstract

Coronary microvascular dysfunction (DMK) is a condition of patients who are accompanied by complaints of chest pain where the results of coronary angiography examination are normal and this is almost 49% with 60% of patients diagnosed with DMK. Another study said that about 40% of patients with DMK showed coronary flow reserve (CFR <2) of about 40% and the WISE study (Women's Ischaemia Syndrome Evaluation) showed that about 47% of patients with chest pain had normal coronary arteries. DMK can be divided into 4 groups; DMK with no coronary arterial disease (CAD) obstruction and myocardial disease, DMK with myocardial disease where this occurs due to remodeling of intramural coronary arteries, DMK with CAD (coronary arterial disease) or acute myocardial infarction with or without ST segment, iatrogenic typhoid DMK occurs after coronary recanalization caused by vasoconstriction and distal embolization. The mechanism of action of DMK can be caused by several factors, namely endothelial dysfunction, smooth muscle dysfunction, decreased diastolic perfusion time, damage to blood vessels and damage to the vascular and microvascular remodeling. And to enforce this DMK, there are several tests carried out in diagnosing the disease, some of which are invasive and non-invasive so that by enforcing the diagnosis of this disease, treatment for DMK can be done immediately and optimally.

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Journal Info

Abbrev

bsm

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

Description

This journal welcomes the submission of articles that offering a sensible transfer of basic research to applied clinical medicine. BioScientia Medicina covers the latest developments in various fields of biomedicine with special attention to : 1.Rhemumatology 2.Molecular aspect of Indonesia ...