Journal of Anesthesiology and Clinical Research
Vol. 2 No. 1 (2021): Journal of Anesthesiology and Clinical Research

The Effectiveness of Mometasone Spray and Triamcinolone Acetonide Gel in Preventing Sore Throat, Cough, and Hoarse after Intubation

Zentika. I. Fajri (Resident of Department of Anesthesiology and Intensive Therapy, Faculty of Medicine Universitas Sriwijaya, Mohammad Hoesin Hospital, Palembang, Indonesia)
Fredi Heru Irwanto (Consultant of Department of Anesthesiology and Intensive Therapy, Faculty of Medicine Universitas Sriwijaya, Mohammad Hoesin Hospital, Palembang, Indonesia)
A Miarta (Department of Pharmacology, Faculty of Medicine Universitas Sriwijaya, Palembang, Indonesia)
Theodorus (Department of Pharmacology, Faculty of Medicine Universitas Sriwijaya, Palembang, Indonesia)



Article Info

Publish Date
09 Dec 2021

Abstract

Background: Endotracheal intubation is a procedure performed by inserting an endotracheal tube into the airway. With endotracheal intubation, there can be several complications ranging from mild to severe. Sore throat, coughing, and hoarseness were several endotracheal intbation complications. From several studies, it was found that the incidence of POST was 21-65%. This study aimed to determine the efficacy between 0.1% triamcinolone acetonide gel and 100 mcg mometasone spray in reducing sore throat, cough, and hoarseness due to endotracheal intubation. Method: A Randomized Controlled Trial, Open-Label was carried out on patients undergoing endotracheal intubation with general anesthesia in RSMH operating room from September 2020 - November 2020. Seventy-two study subjects met the inclusion criteria and were divided into two groups, namely the triamcinolone acetonide gel group, and the mometasone spray group. Analyzing data was SPSS version 23. Result: There were no difference between age, sex, ASA PS classification, and length of operation between the two groups (p> 0.05). Mometasone spray 100 mcg and triamcinolone acetonide gel 0.1% had the same effectiveness to reduce endotracheal intubation such as sore throat, cough, and hoarseness within 24 hours of endotracheal intubation (p> 0.05). There was a significant difference in the incidence of sore throat between two groups in the first hour (p = 0.039). Conclusion: There was no statistically significant difference between the efficiency of mometasone spray 100 mcg and triamcinolone acetonide gel 0.1% on a sore throat, cough, and hoarseness within 24 hours of endotracheal intubation (p > 0.05).

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Journal Info

Abbrev

JACR

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

Description

Journal of Anesthesiology and Clinical Research/JACR that focuses on anesthesiology; pain management; intensive care; emergency medicine; disaster management; pharmacology; physiology; clinical practice research; and palliative ...