Jurnal Sains dan Kesehatan
Vol. 4 No. 1 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)

Uji Efek Tonikum Ekstrak Etanol Daun Pecut Kuda (Stachytarpheta jamaicensis L. Vahl) pada Mencit Putih Jantan (Mus musculus): The Tonicum Effect of Ethanolic Extract of Stachytarpheta jamaicensis Leaves in White Mice Male (Mus musculus)

Yuliawati Yuliawati (Universitas Jambi)
Rofifah Dhia Savira (Universitas Jambi)
Diah Tri Utami (Universitas Jambi)



Article Info

Publish Date
28 Feb 2022

Abstract

Tonic is a substance that can increase the bodys defense system. The stimulant effect that is intertwined with the tonic effect is carried out by the central nervous system. Pecut kuda leaf and bases are useful as stimulants and tonics. This research aims to determine the tonicum effect of ethanolic extract pecut kuda leaf in mice. This was an experimental study with completely randomized group design, using male white mice and divided into five namely two control groups (K- given Na CMC 0,5% and K+ given 13 mg caffeine) and three treatment groups (ethanolic axtract of pecut kuda with a dose 50, 100 and 200 mg/kgBW) and each treatment group was repeated 5 times. The methods used were natatory exhaustion test, hanging test and sleep induction test for the parameters observed were the mice'defense on the surface of the water, the duration of the mice endurance on the hanging device and the time the mice fell asleep.The results of the observation data using Duncan's One Way ANNOVA test. The results showed that the pecut kuda leaf extract was effective against the tonic effect test at doses of 50, 100, 200 mg/kgBW. It can be said that pecut kuda leaf extract at a dose of 200 mg/kgBW has almost the same effect as K+ (13mg caffeine).

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Journal Info

Abbrev

jsk

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Jurnal Sains dan Kesehatan (J. Sains. Kes) (e-ISSN 2407-6082, p-ISSN 2303-0267), is a national journal with ISSN and published four times a year in 2015. In 2016 the publishing frequency changed to twice a year. In 2021 the frequency increased to six times a year. Jurnal Sains dan Kesehatan is ...