VALENSI
Jurnal Kimia VALENSI Volume 8, No. 1, May 2022

Cytotoxic Activity of the Indonesian Fern Angiopteris angustifolia C. Presl and Liverwort Mastigophora diclados (Birs. ex Web) Nees Against Breast Cancer Cell Lines (MCF-7)

Ismiarni Komala (Pharmacy Department Faculty of Health Sciences Universitas Islam Negeri Syarif Hidayatullah Jakarta)
Stevani Sitorus (Pharmacy Department Faculty of Health Sciences Universitas Islam Negeri Syarif Hidayatullah Jakarta)
Fitri Ratna Dewi (Pharmacy Department Faculty of Health Sciences Universitas Islam Negeri Syarif Hidayatullah Jakarta)
Nurmeilis Nurmeilis (Pharmacy Department Faculty of Health Sciences Universitas Islam Negeri Syarif Hidayatullah Jakarta)
Laifa Annisa Hendarmin (Medical Biology Department, Faculty of Medicine, UIN Syarif Hidayatullah Jakarta)

Article Info

Publish Date
30 May 2022

Abstract

Breast cancer is the most frequent cancer among women worldwide, and it is also the main cause of death from cancer. Fern Angiopteris angustifolia C. Presl and Liverwort Mastigophora diclados (Birs.ex Web) Nees are the plants that grow in Indonesia that are limited explored for their phytochemical and biological activity. This study aims to evaluate the cytotoxic effect of ethanolic extracts leaves of A. angustifolia and M. diclados against breast cancer cell lines (MCF-7). The MTT assay was used to determine cytotoxic activity, which revealed that the ethanol extract of A. Angustifolia and M. diclados exhibited cytotoxic activity with an IC50 value of 121.8 ± 13.3 and 29.2 ±1.4 µg /mL, respectively.

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Journal Info
VALENSI
Website

Abbrev

valensi

Publisher

Universitas Islam Negeri Syarif Hidayatullah Jakarta

Subject

Chemistry

Description

Jurnal Kimia Valensi is a biannual and peer-reviewed open access journal published by Department of Chemistry, Faculty of Science and Technology UIN Syarif Hidayatullah Jakarta. This journal covering all aspect of ...