Budapest International Research in Exact Sciences (BirEx Journal)
Vol 4, No 3 (2022): Budapest International Research in Exact Sciences, July

Response Surface Methodology in determining the Temperature and Drying Time of Lactobacilus Casei Probiotic Granules

Sri Nevi Gantini (Unknown)
Ari Widayanti (Unknown)

Article Info

Publish Date
05 Jul 2022

Abstract

Lactobacillus casei is a probiotic bacteria that has an important role in maintaining body health, but its use in liquid preparations is still constrained by shelf life. This study aims to determine the effect of temperature and drying time of wet granulation method on the physical and viability of probiotic granules. This research begins with increasing bacterial biomass and then harvesting the bacteria using centrifuge. Bacteria are encapsulated using 2% alginate and mannitol as fillers. It was dried at a temperature and time variation of 13 test formulas that had been designed by central composite design. The optimal temperature and drying time of probiotic granules obtained from Response Surface Methodology is 45 ° C for 2 hours.

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Journal Info
Budapest International Research in Exact Sciences (BirEx Journal)
Website

Abbrev

birex

Publisher

Budapest International Research and Critics University Journal

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Physics Transportation

Description

Budapest International Research in Exact Sciences (BirEx-Journal) is a peer reviewed journal published in January, April, July, October welcome research paper in Medical Science, Agriculture Science, Biological Science, Engineering Science and other related areas and it is published in both online ...