Bioscientia Medicina : Journal of Biomedicine and Translational Research
Vol. 6 No. 9 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research

Botanical and Chemical Overview, Traditional Uses and Potential of Anticancer Activity from Several Costus Plants: A Narrative Review

Lina Nafisah (Master Program of Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia/Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia)
Eli Halimah (Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia)
Yoppi Iskandar (Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia)

Article Info

Publish Date
28 Jun 2022

Abstract

Plants in the Costus genus are known to have various activities, starting from an antibacterial agent, anti-inflammatory, antioxidant, anticancer, antidiabetic, and so on. From some previous studies that have been conducted, it is stated that some Costus plants have a high potential to be a prospective anticancer candidate in the future. This review will discuss botanical and chemical overview, traditional uses, and potential anticancer activity of several Costus plants, namely C.speciosus, C.igneus, C.spiralis, and C.pictus. In conclusion, anticancer activity assay was carried out by several methods using various cell cultures resulting in an IC50 value ranging from strong and very strong, with the strongest potency belonging to C.speciosus with an IC50 value of 13.87 µg/ml. In addition, the active phytoconstituent, mainly diosgenin, contributes to the anticancer activity, which also strengthens the potential of Costus plants.

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Journal Info
Bioscientia Medicina : Journal of Biomedicine and Translational Research
Website

Abbrev

bsm

Publisher

HM Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

Description

This journal welcomes the submission of articles that offering a sensible transfer of basic research to applied clinical medicine. BioScientia Medicina covers the latest developments in various fields of biomedicine with special attention to : 1.Rhemumatology 2.Molecular aspect of Indonesia ...