Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi)
Vol 6 No 4 (2022): Agustus 2022

QSAR Study of Larvicidal Phytocompounds as Anti-Aedes Aegypti by using GA-SVM Method

Komang Triolascarya (Telkom University)
Reza Rendian Septiawan (Telkom University)
Isman Kurniawan (Telkom University)



Article Info

Publish Date
22 Aug 2022

Abstract

Aedes aegypti is one of the most dangerous mosquitoes that can cause several deadly diseases, such as dengue fever, Chikungunya, Zika, and jaundice with high mortality rate. For now, no specific drug has been found that can cure the disease caused by Aedes Aegypti. One possible solution for handling this problem is to inhibit the growth and development of Aedes aegypti larvae. This study aims to implement Genetic Algorithm-Support Vector Machine to develop Quantitative Structure-Activity Relationship model for identification larvicidal phytocompounds as anti-aedes-aegypti. Hyperparameter tuning was performed to improve the performance of the models. Based on the result, we found that the best model was developed by the RBF kernel with the value of and score are 0.64 and 0.64, respectively.

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Journal Info

Abbrev

RESTI

Publisher

Subject

Computer Science & IT Engineering

Description

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) dimaksudkan sebagai media kajian ilmiah hasil penelitian, pemikiran dan kajian analisis-kritis mengenai penelitian Rekayasa Sistem, Teknik Informatika/Teknologi Informasi, Manajemen Informatika dan Sistem Informasi. Sebagai bagian dari semangat ...