ZAHRA: JOURNAL OF HEALTH AND MEDICAL RESEARCH
Vol. 2 No. 3 (2022): JULI

PENAMBATAN MOLEKUL DAN PREDIKSI UJI TOKSISITAS PADA SENYAWA TURUNAN INHIBITOR GATA-2 SEBAGAI PENINGKAT TRANSKRIPSI ERITROPOIESIS

Dona Suzana (Program Studi Farmasi, Fakultas Ilmu Kesehatan dan Farmasi, Universitas Gunadarma, Indonesia)
Ashfar Kurnia (Program Studi Farmasi, Fakultas Ilmu Kesehatan dan Farmasi, Universitas Gunadarma, Indonesia)
Dina Melia Oktavilantika (Program Studi Farmasi, Fakultas Ilmu Kesehatan dan Farmasi, Universitas Gunadarma, Indonesia)
Lathvi Masyithah (Program Studi Farmasi, Fakultas Ilmu Kesehatan dan Farmasi, Universitas Gunadarma, Indonesia)

Article Info

Publish Date
04 Aug 2022

Abstract

Anemia is a condition in which the number of red blood cells or the amount of hemoglobin, a protein responsible for transporting oxygen throughout the body, is below normal. The condition of chronic kidney disease causes a decrease in hemoglobin levels in the body so that it affects the proliferation of red blood cells. The search for compounds to stimulate the process of red blood cell proliferation without involving erythropoietin was carried out. Pyrrotiogatain compounds are believed to increase the proliferation of red blood cells, but are reported to have serious toxicity. Then modification of the molecule is carried out to find the effectiveness which has lower toxicity. Several pyritiogartain derivatives have been produced which are effective with molecular tethering and determination of the productive toxicity.

Copyrights © 2022




Citation Download
RIS
EndNote, Reference Manager, ProCite
BibTex
Latex, Jabref
Full PDF
557.652 KB
Original Source
Download Original
Google Scholar
Check in Google Scholar
Journal Info
ZAHRA: JOURNAL OF HEALTH AND MEDICAL RESEARCH
Website

Abbrev

aisha

Publisher

CV. Adiba Aisha Amira

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

This Journal focuses on health sciences, including preventive, promotive, curative, and rehabilitative fields, by publishing "original articles" and "review articles." The scientific scope of the Health Scientific Journal include Medical and clinical research, Public health research (health ...