The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Vol 21, No 1 (2020): VOLUME 21, NUMBER 1, April 2020

C-Reactive Protein and Interleukin-6 Correlated with Resistin Level in Liver Cirrhosis

I Ketut Mariadi (Division of Gastroentero-hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, Sanglah General Hospital, Denpasar)
Hendra Koncoro (Department of Internal Medicine, Faculty of Medicine, Universitas Udayana/Sanglah General Hospital, Denpasar)
I Dewa Nyoman Wibawa (Division of Gastroentero-hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Udayana/Sanglah General Hospital, Denpasar)



Article Info

Publish Date
26 Jul 2020

Abstract

Background: The incidence of insulin resistance is very high in liver cirrhosis. Resistin is thought to be one of the factors contributing to the occurrence of insulin resistance. Liver Cirrhosis is a chronic inflammatory condition. C-reactive protein (CRP) and interleukin-6 (IL-6) are inflammatory mediators, which are associated with the severity of liver damage. Resistin also increases in liver cirrhosis. This study aimed to determine whether CRP and IL-6 levels were correlated with resistin levels in patients with liver cirrhosis.Method: An analytic cross-sectional study was conducted, in cirrhosis patients, to determine CRP and IL-6 levels as markers of the inflammatory process and blood resistin levels.Results: In this study was found, CRP and IL-6 levels were associated with the severity of liver cirrhosis. Resistin levels are associated with the severity of cirrhosis of the liver. CRP and IL-6 levels are positively correlated with resistin levels and as independent predictors of resistin levels.Conclusion: This study concluded that CRP and IL-26 levels are correlated with resistin levels and as independent predictors of resistin levels in liver cirrhosis patients.

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Journal Info

Abbrev

jghe

Publisher

Subject

Medicine & Pharmacology

Description

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive ...