This research aimed to determine the effect of Trichoderma sp dosage and cow manure dosage on the growth and yield of cayenne pepper. The research used a randomized block design with three replications. The factors studied were the dose of Trichoderma with three levels, namely T0 (Trichoderma dose of 0 g / polybag), T1 (Trichoderma 0.5 g / polybag), and T2 (Trichoderma 1 g / polybag), as well as the dosage factor of cow manure with four levels are P0 (cow manure dose 0 g / polybag) P1 (cow manure 125 g / polybag), P2 (cow manure 250 g / polybag) and P3 (cow manure 375 g / polybag). The variables studied were plant height, stem base diameter, number of leaves, number, number of fruits, the weight of fruit crops, and production of tonnes/ha. The results showed that the treatment dose of Trichoderma T0 (without Trichoderma), T1 (Trichoderma dose of 0.5 g / polybag), and T2 (Trichoderma 1 g / polybag) had no significant effect on all plant parameters, while the dose treatment of cow manure in treatment P0 (without cow manure) significantly different from treatment P1 (cow manure 125 g / polybag), P2 (cow manure 250 g / polybag), and P3 (cow manure 375 g / polybag). There was no interaction between doses of Trichoderma with the dose of cow manure on the growth and yield of cayenne pepper
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