Indonesian Journal of Cancer
Vol 16, No 4 (2022): December

Resection of Anaplastic Meningioma via Combined Craniofacial Approach

Yosafat Kurniawan Sugiarto (Faculty of Medicine, Tarumanagara University, Jakarta)
Arwinder Singh (Department of Neurosurgery, Dharmais Cancer Hospital - National Cancer Center, Jakarta)
Muhammad Firdaus (Department of Neurosurgery, Dharmais Cancer Hospital - National Cancer Center, Jakarta)
Oskar Ady Widarta (Department of Neurosurgery, Dharmais Cancer Hospital - National Cancer Center, Jakarta)
Farilaila Rayhani (Department of Anatomical Pathology, Dharmais Cancer Hospital - National Cancer Center, Jakarta)



Article Info

Publish Date
28 Dec 2022

Abstract

Introduction: Meningiomas are common and mostly benign intracranial tumors but may show a histological progression to malignancy. The mechanism of malignant transformation remains unclear. Malignant meningiomas usually bear a high recurrence rate and unfavorable prognosis; hence, multiple surgical resections are required for the treatmentCase Presentation: A 41-year-old woman with a prior history of craniotomy at another center six years ago with Meningioma Grade 1 presented to our institution with new neurological symptoms. The magnetic resonance image demonstrated a large frontal base mass that extended to the nasal cavity with diffuse contrast enhancement and extensive surrounding edema. A craniofacial approach combined with a bifrontal approach was performed in multistage tumor resection. The tumor and the infiltrated dura were radically removed. The histopathology demonstrated an Anaplastic Meningioma. The patient also underwent radiation therapy.Conclusion:  Treatment of recurrent meningioma with anaplastic histology remains challenging because recurrence rates remain high with a poor prognosis.

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Journal Info

Abbrev

ijoc

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Indonesian Journal of Cancer is a peer-reviewed and open-access journal. This journal is published quarterly (in March, June, September, and December) by Dharmais Cancer Hospital - National Cancer Center. Submissions are reviewed under a broad scope of topics relevant to experimental and clinical ...