Journal of Global Pharma Technology
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Synthesis and Spectral Study of mono-ligand Complexes for Acriflavine with Some Metalions and Evaluation Their Antibacterial Activity

Haya H. Abdul. Hameed (Unknown)



Article Info

Publish Date
30 Mar 2018

Abstract

In this study, a new seven complexes have been prepared from acriflavine (LCl) with metal ions VO (II),Co (II),Ni (II),Cu (II) ,Cd (II), Zn (II) and Hg (II) with mole ratio (M:L) (2:2) all complexes have general composition [M2(L1)Cl4(H2O)4]Cl2, [(VO)2(L1)2(SO4)2(H2O)2]Cl2in ethanol. The ligand and all complexes were characterized by modern spectroscopic(IR, UV_Vis , Mass, atomic absorption), along with elemental microanalysis, magnetic susceptibility measurements and molar conductance. In addition to evaluated their antibacterial activity against two type of bacterial. Based on date for all techniques we suggested that all the prepared complexes have octahedral geometry, the value of antibacterial activity of this prepared complexes showed higher inhibition activity compared to the free ligandKeywords: Acriflavine, Acridine, Acriflavine metal complexes, Biological activity.

Copyrights © 2018






Journal Info

Abbrev

jgpt

Publisher

Subject

Medicine & Pharmacology

Description

ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and ...