Jurnal Ilmu Kedokteran (Journal of Medical Science)
Vol 17, No 1 (2023): Jurnal Ilmu Kedokteran

Vaksin Terapeutik yang Menargetkan Onkoprotein E6 dan E7 pada Kanker Serviks

Maya Savira (Universitas Riau [SCOPUS ID: 57201445176])

Article Info

Publish Date
08 May 2023

Abstract

Cervical cancer is caused by persistent high-risk type of human papillomavirus (HPV) infection. especially types 16 and 18. The choice of cervical cancer therapy is associated with many side effects, tumor drug resistance, and high costs. A more efficient, safe and effective cervical cancer therapy is needed, such as therapeutic vaccine which targets host factors related to E6 and E7 of HPV oncoprotein. The oncoprotein E6 targets and inhibits p53, whereas E7 inhibits pRb. Therapeutic vaccines can be used to treat cervical cancer in all stage. Currently, this therapeutic vaccine is under investigation in phase I/II/III clinical trials.

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Journal Info
Jurnal Ilmu Kedokteran (Journal of Medical Science)
Website

Abbrev

jik

Publisher

Universitas Riau

Subject

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

Description

Journal of Medical Science receives a script from health and medical lecturer, undergraduate, residents, hospital staff and those who interested in writing scientific papers. The scientific articles posted on JIK include: literature reviews, research article, case report and EBCR (Evidence Based ...