Fullerene Journal of Chemistry
Vol 8 No 1 (2023): Fullerene Journal of Chemistry

Synthesis of Iodo Quinolinone

Stefan Marco Rumengan (Universitas Negeri Manado)
Khoirotul Ummah (Universitas Islam Negeri Sunan Ampel)



Article Info

Publish Date
27 May 2023

Abstract

Quinolones are important heterocyclic compounds in medicine and materials for DSSC or OLED. This study aims to make a quinolinone framework that has several functional groups. These functional groups can be coupled with various other heterocyclic compounds. The synthesis of the target compound consists of forming a quinolinone framework using phenyldiamine and ethyl aceto acetate via the Penchmann reaction then iodination using ICl. The Penchmann reaction succeeded in forming a quinolinone framework as indicated by shown a proton signal at 11.22 ppm. The iodination reaction was successfully carried out by adding iodo to the benzene ring and the appearance peak of (M+H) m/z was 300.9839 on mass spectroscopy. The compound 7-amino-8-iodo-4-methyl-2-quinolinone (compound 2) has been successfully synthesized. Compound 2 has 3 functional groups (amine, iodo and alkene) that can be used for coupling with the other heterocycles.

Copyrights © 2023






Journal Info

Abbrev

fulerene

Publisher

Subject

Chemistry

Description

Fullerene Journal Of Chemistry is an chemistry indonesian journal presented by chemistry department, State University of ...