Jurnal Surya Medika
Vol. 9 No. 1 (2023): Jurnal Surya Medika (JSM)

Uji Aktivitas Antiinflamasi Ekstrak Batang Karamunting (Rhodomyrtus tomentosa) Terhadap Tikus Jantan Galur Wistar: Test of Antiinflamatory Activity Extract of Karamunting (Rhodomyrtus tomentosa) Stem to Male Rat Wistar Strain

Rika Arfiana Safitri (Universitas Muhammadiyah Palangka Raya)
Mamik Ponco Rahayu (Universitas Setia Budi Surakarta)
Gunawan Pamudji Widodo (Universitas Setia Budi Surakarta)



Article Info

Publish Date
27 Apr 2023

Abstract

Inflammation is a response to tissue damage due to various adverse stimuli, both chemical and mechanical, infections and foreign bodies such as bacteria and viruses. This study aims to determine the effect of the anti-inflammatory effect of ethanol extract of karamunting stems. Karamunting stems were extracted by maceration method using 96% ethanol solvent. Each anti-inflamatory test was divided into five groups, namely the negative control group (CMC Na), the positive control group (Diclofenac Na), the Karamunting stem extract test group (dose of 100 mg/kg BW, 200 mg/Kg BW, and 400 mg/kg). kg BW). Anti-inflammatory test using the Rat hind paw edema method induced by 1% carrageenan. Data analysis used the Shapiro-Wilk test and then continued with a one-way ANOVA test. The results showed that the ethanol extract of karamunting stems had an anti-inflammatory effect at doses of 200 mg/Kg BW and 400 mg/Kg BW.the karamunting stem could provide an analgesic effect at a dose of 200 mg/Kg BW.

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Journal Info

Abbrev

jsm

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

The publication of Jurnal Surya Medika certainly participates in disseminating the results of research and review of science and technology development conducted by lecturers and researchers especially from UM Palangkaraya and other universities. This edition contains 17 articles consisting of ...