Jurnal Kedokteran Gigi Terpadu
Vol. 5 No. 1 (2023): Jurnal Kedokteran Gigi Terpadu

Aktivitas Antioksidan Ekstrak Etanol Bunga Clitoria ternatea L. Dengan Senyawa Antioksidan (Antosianin dan Mirisetin)

Monica Dewi Ranggaini (Departemen Biologi Oral, Fakultas Kedokteran Gigi Universitas Trisakti)
Johni Halim (Departemen Biologi Oral, Fakultas Kedokteran Gigi Universitas Trisakti)
Intan Paramitha Kumaladevi (Mahasiswa, Fakultas Kedokteran Gigi Universitas Trisakti)



Article Info

Publish Date
04 Jul 2023

Abstract

Background: The COVID-19 pandemic is impacting a large number of populations. Patients with cancer infected with this virus require a longer treatment. Cancer occurs due to oxidative stress which creates an imbalance between the production of reactive oxygen species (ROS) and the amount of antioxidants in the body. Antioxidants are needed to balance ROS and increase the body's resistance to infection and disease. Clitoria ternatea L. is known to be one of the natural ingredients that has the potential as a natural antioxidant. It contains active compounds, such as anthocyanin and myricetin which act as antioxidants. Purpose: To find out the comparison of antioxidant activity C. ternatea L. extract in ethanol 70% solvent with the antioxidant compounds of anthocyanin and myricetin. Method: Research with laboratory experimental methods. C. ternatea L. simplicia was extracted using maceration method in 70% ethanol solvent. Antioxidant activity test using the 2,2-diphenyl-l-picrylhydrazyl (DPPH) method was carried out on samples of C. ternatea L. ethanol extract, anthocyanin and myricetin antioxidant compounds with a wavelength of 517 nm to measure their absorbance using a microplate reader. Result: The IC50 value of the ethanol extract of C. ternatea L. was 52.40 mg/mL, the antioxidant compound anthocyanin was 27.68 mg/mL and the antioxidant compound myricetin was 4.89 mg/mL. Conclusion: The antioxidant compound myricetin has very strong antioxidant activity compared to the ethanol extract of C. ternatea L. and the antioxidant compounds of anthocyanins.

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Journal Info

Abbrev

jkgt

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Jurnal Kedokteran Gigi Terpadu publishes articles and scientific work from Researches, Case Reports and Literature Reviews in Dentistry and Dental Science. The scopes vary from: Dental Surgery, Dental Forensics, Oral Biology, Oral Medicine, Dental Public Health and Preventive Dentistry, Paediatric ...