MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan
Vol 10, No 2 (2023): August

Antibacterial Effects of Garlic Ethyl Acetate Fraction (Allium Sativum L.) on the Growth Of Bacteria Staphylococcus aureus and Escherichia coli

Larasati Juninda (Universitas Muhammadiyah Surakarta, Central Java, Indonesia)
Listiana Masyita Dewi (Universitas Muhammadiyah Surakarta, Central Java, Indonesia)
Retno Sintowati (Universitas Muhammadiyah Surakarta, Central Java, Indonesia)
Rochmadina Suci Bestari (Universitas Muhammadiyah Surakarta, Central Java, Indonesia)



Article Info

Publish Date
06 Aug 2023

Abstract

Background: Antibiotics are a treatment used to treat bacterial infections. However, the many antibiotic-resistant bacteria caused researchers to use plants as an alternative treatment, one of which is garlic (Allium sativum L.).Objective: Previous research stated that the diameter of the inhibition zone by garlic had a more excellent value than the antibiotics used. Hence, the researchers were interested in conducting an antibacterial test of the ethyl acetate fraction of garlic against the growth of Staphylococcus aureus and Escherichia coli.Methods: This study was an experimental laboratory using the posttest-only control group design method in the Kruskal Wallis test data analysis.Results: the results of the inhibition analysis with p-value < 0.05 in each test group for both Staphylococcus aureus and Escherichia coli. With the Mann-Whitney test, the results obtained a p-value <0.005 for each bacteria and test group. The most significant value, namely p= 0.002. This result shows significant differences between the test groups for each bacterium.Conclusion: There is an antibacterial effect of the ethyl acetate fraction of garlic (Allium sativum L.) at concentrations of 25%, 50%, and 100% against the growth of Staphylococcus aureus and Escherichia coli

Copyrights © 2023






Journal Info

Abbrev

APKKM

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Magna Medica is a medical journal of APKKM contains papers and scientific articles created as a form of realization Tridharma college. The journal is published every six months, April and October of three articles in the form of: - Research article - Case report - Literature review The scope of this ...