Dengue Hemorrhagic Fever (DHF) is an endemic disease that causes high morbidity and mortality rates. Globally, dengue fever is reported to range from 1-3 million cases while the number of deaths ranges from 2-4 thousand in the last decade. The prevalence of DHF in Indonesia in 2018 reached 24.75 per 100,000 and in South Kalimantan in 2019 it reached 56.83 per 100,000 population. One of the efforts to control dengue vectors is the use of larvicides. The purpose of this study was to determine the potential of Srigading Plants (Nyctanthes arbor-tristis) as Aedes aegypti larvae as vectors of DHF in Wetlands. This study used a true experimental research design using the post test only controlled group design to determine the effectiveness of Srigading extract (Nyctanthes arbor-tristis) against the death of Aedes aegypti instar IV mosquito larvae. Based on the results of the one way ANOVA test, a significance value or p-value of 0.0001 0.05 was obtained, which indicated that there was a significant difference between the number of mosquito larvae deaths and the concentration of Srigading extract given.Based on the results of the post-hoc test using LSD, it was found that there was a significant difference between the Srigading extract and the control group. The comparison found between the negative control and the concentration was found at a concentration of 3588 ppm, at that concentration there was a significant difference. There is one concentration of Srigading leaf extract (Nycthanthes arbor-tritis) which has larvicidal activity, that is a concentration of 3588 ppm.
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