Typhoid fever is an infectious disease caused by the bacterium Salmonella typhi which is still common and frequently occurring. Indonesia is an endemic country for typhoid fever, with an estimated 800 cases per 100,000 population annually. The risk factors for typhoid fever include personal hygiene such as nail cleanliness, handwashing, dietary habits, and others. The aim of this study was to determine how personal hygiene affects the number of typhoid fever cases at RS TNI AU dr. Charles P.J Suoth in Manado city. This research used a descriptive analytic method with a cross-sectional approach. The instrument used in this study was a questionnaire. The data obtained were analyzed using the Chi-square test. The results of the study showed that the majority of subjects were aged >25 years (45.8%), with females being more susceptible (51.0%), unemployed individuals (19.8%), and with a middle level of education (39.6%). Bivariate analysis revealed a significant association between the habit of handwashing with soap after defecation and a p-value of 0.002. There was an association between the frequency of typhoid fever and the habit of washing raw food with soap before eating, history of direct contact with typhoid patients, and handwashing before meals.
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