Jurnal Sains dan Kesehatan
Vol. 6 No. 2 (2024): J. Sains Kes.

Antimicrobial Activity Test of Ethanol Extract of Senggani Leaves (Melastoma malabraticum L) Against Propionibacterium Acnes and Staphylococcus Epidermidis

Haris Munandar Nasution (Faculty of Pharmacy, Universitas Muslim Nusantara Al Washliyah, Medan, Indonesia)
Zulmai Rani (Faculty of Pharmacy, Universitas Muslim Nusantara Al Washliyah, Medan, Indonesia)
Ziza Putri Aisyia Fauzi (Faculty of Pharmacy, Universitas Muslim Nusantara Al Washliyah, Medan, Indonesia)
Ahmad Rasyid Ridho (Faculty of Pharmacy, Universitas Muslim Nusantara Al Washliyah, Medan, Indonesia)



Article Info

Publish Date
30 Apr 2024

Abstract

Senggani leaves are a plant that can be found in Indonesia, including hilly locations. The people of Marendal, Patumbak subdistrict, believe that senggani leaves may heal minor skin wounds. The goal of this study was to identify the class of secondary metabolite chemical compounds and their antibacterial efficacy against the microorganisms Propionibacterium acnes and Staphylococcus epidermidis at 5, 10, and 20% concentrations. The ethanol extract of senggani leaves contains secondary metabolite compounds with antibacterial activity. According to the antibacterial test results, a 20% ethanol extract of senggani leaves is effective against Propionibacterium with a diameter of 10.7 mm, a 10% in the medium category with a diameter of 9.27 mm, and a 5% in the medium category with a diameter of 8.8 mm. Meanwhile, the diameter of Staphylococcus epidermidis at a 20% was 8.77 mm in the medium category, 8.37 mm at 10%, and 8.6 mm at a 5% concentration.   Keywords:          Propionibacterium acnes, Senggani leaves, Staphylococcus epidermidis

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Journal Info

Abbrev

jsk

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Jurnal Sains dan Kesehatan (J. Sains. Kes) (e-ISSN 2407-6082, p-ISSN 2303-0267), is a national journal with ISSN and published four times a year in 2015. In 2016 the publishing frequency changed to twice a year. In 2021 the frequency increased to six times a year. Jurnal Sains dan Kesehatan is ...