Jurnal Farmasi dan Sains Indonesia (JFSI)
Vol 7 No 1 (2024)

Uji Efektivitas Penyembuhan Luka Bakar dari Sediaan Gel Ekstrak Daun Jarak Pagar (Jatropha Curcas L) pada Tikus Putih Jantan (Rattus Norvegicus)

Ivan Mesak (Institut Ilmu Kesehatan STRADA Indonesia)
Odilia Dea Christina (Sekolah Tinggi Ilmu Farmasi Nusaputera)
Angelina T.I. (Institut Ilmu Kesehatan STRADA Indonesia)



Article Info

Publish Date
20 Jun 2024

Abstract

The occurrence of burns on the skin is a type of injury that requires fast and appropriate treatment in order to achieve an optimal level of healing. Handling burns using medicinal plants can be done. One of the plants that can be used is Jatropha leaves. Jatropha leaves contain active substances such as saponins, tannins, alkaloids, and flavonoids that are efficacious as antibacterial, antioxidant, anticancer and antiinflammatory. The purpose of this study was to determine the effectiveness of Jatropha curcas leaf extract gel preparations with concentrations of 10%, 15%, 20% on burn wound healing. This study is an experimental study by comparing the effectiveness of burn wound healing in rats in each test group, namely negative control given gel base, positive control given Bioplacenton gel, and three test control groups with each given Jatropha leaf extract gel concentrations of 10%, 15% and 20%. The test results show that the most effective Jatropha leaf extract gel preparation heals rat burns, namely the 20% concentration compared to the positive control with a P>0.914 value (P>0.05).

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Journal Info

Abbrev

jfsi

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience

Description

Focus and Scope Jurnal Farmasi & Sains Indonesia is an open-access journal that published twice a year by Sekolah Tinggi Ilmu Farmasi Nusaputera. This journal is a media of research publication on all aspects of pharmaceutical & science that is innovative, creative, original and based on scientific. ...