INDONESIAN JOURNAL OF PHARMACY
Vol 27 No 1, 2016

ANTIOXIDANT, ANTIBACTERIAL POTENTIAL AND HPLC ANALYSIS OF Dioscorea alata BULB

Md. Anisuzzman - - (Science School, Khulna University, Khulna-9208)
Md. Nazmul Hasan Zilani (Science School, Khulna University, Khulna-9208)
Sharmin Sultana Khushi (Fisheries and Marine Resource Technology Discipline, Khulna University, Khulna, 9208)
Md. Asaduzzman - -- (Department of Fisheries, Sylhet Agricultural University, Sylhet)
Md. Golam Hossain - (Science School, Khulna University, Khulna-9208)

Article Info

Publish Date
01 Jan 2016

Abstract

  The purpose of the present study was to evaluate antioxidant, antibacterial potential and HPLC analysis of methanol extract of Dioscorea alata bulb. Antioxidant activity investigated by DPPH free radical scavenging assay, the IC50 value of plant extract was24.99µg/mL. Significant absorption of extract (1.317 of 1mg/mL) showed the ferric reducing activity. HPLC analysis indicated the presence of myricetin (471.53mg/100 g of dry extract) in the highest concentration. Extract showed significant zone of inhibition in antibacterial activity test. The presence of myricetin along with other detected polyphenols might contribute to antioxidant and antibacterial activities. Key words: Total Phenolic content, Myricetin, Scavenging activity, Disc diffusion

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Journal Info
INDONESIAN JOURNAL OF PHARMACY
Website

Abbrev

3

Publisher

Universitas Gadjah Mada

Subject

Medicine & Pharmacology

Description

Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas ...