Sanus Medical Journal
Vol. 4 No. 1 (2022)

Karakteristik Mutasi EGFR pada Pasien Kanker Paru Jenis Adenokarsinoma yang Diterapi dengan Tyrosien Kinase Inhibitor (TKI) di Rumah Sakit Paru Dr. H.A Rotinsulu Bandung

Puspita, Desi (Unknown)
Dwi Astuti, Vitri (Unknown)
Rina (Unknown)
Sampurno, Edi (Unknown)

Article Info

Publish Date
28 Feb 2022

Abstract

This descriptive study describes the proportion of Epidermal Growth Factor Receptor (EGFR) mutations in lung cancer Adenocarcinoma patients at Rumah Sakit Paru (RS Paru) Dr. H. A Rotinsulu Bandung in the range of 2018 to 2020. EGFR mutations were examined using RGQ thera screen technology Real"‘Time Polymerase Chain Reaction from FFPE or cytology smear. There are 44 data point mutations after examining the EGFR mutation. 59% cases were 40"‘60 years old group dan 52 % were female. It was found that in this group 86% patient with single mutation and 16% had doube mutations. EGFR mutations occurred in Exon 21 L858R in 13 cases (30 %), Exon 21 L861Q in 1 case (2%), Exon 19del in 24 cases (55%), double mutation Exon 19 and Exon 20 T790M type in 2 cases (4%), double mutation Exon 19del and Exon 21 in 4 cases (9%).

Copyrights © 2022




Citation Download
RIS
EndNote, Reference Manager, ProCite
BibTex
Latex, Jabref
Original Source
Download Original
Google Scholar
Check in Google Scholar
Journal Info
Sanus Medical Journal
Website

Abbrev

smj

Publisher

Universitas Muhammadiyah Prof. Dr. Hamka

Subject

Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Description

Sanus Medical Journal is a peer-reviewed medical and health journal published periodically every six months. Sanus Medical Journal publishes descriptive, analytical, and experimental studies, reviews, systematic reviews, case reports, letters, and editorials in the fields of Medicine, Health, ...