Journal of Dentomaxillofacial Science
Vol. 13 No. 2 (2014): Formerly Jurnal Dentofasial ISSN 1412-8926

Hubungan kualitas darah dengan konsentrasi transforming growth factor-β pada platelet rich plasma yang digunakan untuk regenerasi tulang dan jaringan periodontal (Correlation of blood quality with concentration of transforming growth factor-ß1 in platelet rich plasma for bone and periodontal tissue regeneration)

Surijana Mappangara (Bagian Bedah Mulut Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, Indonesia)
Burhanuddin DP (Bagian Ilmu Kesehatan Gigi Masyarakat Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, Indonesia)
Arni Irawaty Djais (Bagian Periodontologi Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, Indonesia)



Article Info

Publish Date
30 Jun 2014

Abstract

This study aimed to explore the correlation of blood quality with transforming growth factor (TGF-ß1) of platelet richplasma (PRP) which was used for bone and periodontal tissue regeneration. Thirty nine subjects participated in thisstudy. Data of age, gender, eritrocyt, leucocyt, hemoglobin, thrombocyt, and TGF-ß1 concentration were used toanalyze the correlation using Spearman correlation test. This study found leucocyt, eritrocyt, hemoglobin, thrombocytconcentration mean was 8.19 g/dl, 5.31 g/dl, 14.48 g/dl, 326.32 g/dl, respectively. The TGF-ß1 concentration meanacquired from PRP was 31994.27 pg/ml. Based on Spearman correlation test, significant correlation was onlyobserved in eritrocyt concentration variable with p value 0.023 (p<0.05) and it was higher in male than in female. It was concluded that TGF-ß1 concentration in PRP from normal subject was 31994.27 pg/ml. Based on leucocyt,eritrocyt, hemoglobin, and thrombocyt test to TGF-ß1, only eritrocyt showed the significant relationship. This findingalso showed the linear correlation between the amoung of eritrocyt in blood with TGF-ß1 as the increased eritrocytvalue was followed by the excalated TGF-ß1 value.

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Journal Info

Abbrev

jdmfs

Publisher

Subject

Dentistry

Description

Journal of Dentomaxillofacial Science (J Dentomaxillofac Sci) is an international, peer-reviewed, and open access journal published in English language. Our journal aims to keep dentists informed of developments and advances in general dentistry and its different specialties in an easy-to-read ...