Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Vol 50, No 1 (2018)

Correlation between Toxoplasma gondii and Cytomegalovirus infections and somatic symptom in community

Isti Anindya (Student of Master Programme, Biomedical Science, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta)
Budi Mulyono (Department of Clinical Pathology Pathology Clinic, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta)
Carla R. Marchira (Department of Psychiatry, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta)
Marsetyawan HNE Soesatyo (Department of Histology and Cell Biology, Faculty of Medicine Universitas Gadjah Mada, Yogyakarta)



Article Info

Publish Date
23 Jul 2018

Abstract

The prevalence of Toxoplasma gondii and Cytomegalovirus (CMV) infections are high in the world. Indonesia is one of the countries with high prevalence of these infections varied from 20 to 63%. The T. gondii and CMV infections infections can be chronic and cause maternal and fetal deatht as well as infant defects. Previous clinical study reported that chronic infections can cause somatic symptoms indicating psychological stress. The aim of this study was to evaluate the correlation between T. gondii and CMV infections with somatic symptoms. This was an observational study with a cross sectional design involving 103 eligible patients with seropositive IgG T. gondii or and CMV from six cities in Java, Indonesia. The presence of somatic symptoms was detected by using somatic symptoms inventory (SSI) questionnaire. Logistic regression analysis was used to evaluate the correlation. The percentage of patients with somatic symptoms (SSI score >48) in seropositive groups of IgG anti- T. gondii, anti-CMV, anti- T. gondii and CMV were 70.0; 62.2 and 36.2%, respectively. In addition, the prevalence ratio (PR) for each group were 1.333, 1.178, and 0.954, respectively. No significantly different in PR was observed in this study (p>0.05). In conclusion, the T. gondii and CMV infections are not correlted with the somatic symptoms.  

Copyrights © 2018






Journal Info

Abbrev

bik

Publisher

Subject

Immunology & microbiology Neuroscience

Description

Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality ...